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Joachim L. Schultze

TitleProf. Dr.
InstitutionUniversity of Bonn
DepartmentGenomics & Immunoregulation, LIMES Institute
AddressBonn 53115
Phone+49 228 73 62787
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Becker M, Schultze H, Bresniker K, Singhal S, Ulas T, Schultze JL. A novel computational architecture for large-scale genomics. Nat Biotechnol. 2020 Sep 30. PMID: 32999473.
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    2. Rajewsky N, Almouzni G, Gorski SA, Aerts S, Amit I, Bertero MG, Bock C, Bredenoord AL, Cavalli G, Chiocca S, Clevers H, De Strooper B, Eggert A, Ellenberg J, Fernández XM, Figlerowicz M, Gasser SM, Hubner N, Kjems J, Knoblich JA, Krabbe G, Lichter P, Linnarsson S, Marine JC, Marioni J, Marti-Renom MA, Netea MG, Nickel D, Nollmann M, Novak HR, Parkinson H, Piccolo S, Pinheiro I, Pombo A, Popp C, Reik W, Roman-Roman S, Rosenstiel P, Schultze JL, Stegle O, Tanay A, Testa G, Thanos D, Theis FJ, Torres-Padilla ME, Valencia A, Vallot C, van Oudenaarden A, Vidal M, Voet T. LifeTime and improving European healthcare through cell-based interceptive medicine. Nature. 2020 Sep 07. PMID: 32894860.
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    3. Rabold K, Aschenbrenner A, Thiele C, Boahen CK, Schiltmans A, Smit JWA, Schultze JL, Netea MG, Adema GJ, Netea-Maier RT. Enhanced lipid biosynthesis in human tumor-induced macrophages contributes to their protumoral characteristics. J Immunother Cancer. 2020 Sep; 8(2). PMID: 32943450.
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    4. Beyer M, Abdullah Z, Chemnitz JM, Maisel D, Sander J, Lehmann C, Thabet Y, Shinde PV, Schmidleithner L, Köhne M, Trebicka J, Schierwagen R, Hofmann A, Popov A, Lang KS, Oxenius A, Buch T, Kurts C, Heikenwalder M, Fätkenheuer G, Lang PA, Hartmann P, Knolle PA, Schultze JL. Publisher Correction: Tumor-necrosis factor impairs CD4+ T cell-mediated immunological control in chronic viral infection. Nat Immunol. 2020 Sep; 21(9):1135. PMID: 32620862.
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    5. Willers M, Ulas T, Völlger L, Vogl T, Heinemann AS, Pirr S, Pagel J, Fehlhaber B, Halle O, Schöning J, Schreek S, Löber U, Essex M, Hombach P, Graspeuntner S, Basic M, Bleich A, Cloppenborg-Schmidt K, Künzel S, Jonigk D, Rupp J, Hansen G, Förster R, Baines JF, Härtel C, Schultze JL, Forslund SK, Roth J, Viemann D. S100A8 and S100A9 are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants. Gastroenterology. 2020 Aug 14. PMID: 32805279.
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    6. Schulte-Schrepping J, Reusch N, Paclik D, Baßler K, Schlickeiser S, Zhang B, Krämer B, Krammer T, Brumhard S, Bonaguro L, De Domenico E, Wendisch D, Grasshoff M, Kapellos TS, Beckstette M, Pecht T, Saglam A, Dietrich O, Mei HE, Schulz AR, Conrad C, Kunkel D, Vafadarnejad E, Xu CJ, Horne A, Herbert M, Drews A, Thibeault C, Pfeiffer M, Hippenstiel S, Hocke A, Müller-Redetzky H, Heim KM, Machleidt F, Uhrig A, Bosquillon de Jarcy L, Jürgens L, Stegemann M, Glösenkamp CR, Volk HD, Goffinet C, Landthaler M, Wyler E, Georg P, Schneider M, Dang-Heine C, Neuwinger N, Kappert K, Tauber R, Corman V, Raabe J, Kaiser KM, Vinh MT, Rieke G, Meisel C, Ulas T, Becker M, Geffers R, Witzenrath M, Drosten C, Suttorp N, von Kalle C, Kurth F, Händler K, Schultze JL, Aschenbrenner AC, Li Y, Nattermann J, Sawitzki B, Saliba AE, Sander LE. Severe COVID-19 Is Marked by a Dysregulated Myeloid Cell Compartment. Cell. 2020 09 17; 182(6):1419-1440.e23. PMID: 32810438.
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    7. Neubert P, Homann A, Wendelborn D, Bär AL, Krampert L, Trum M, Schröder A, Ebner S, Weichselbaum A, Schatz V, Linz P, Veelken R, Schulte-Schrepping J, Aschenbrenner AC, Quast T, Kurts C, Geisberger S, Kunzelmann K, Hammer K, Binger KJ, Titze J, Müller DN, Kolanus W, Schultze JL, Wagner S, Jantsch J. NCX1 represents an ionic Na+ sensing mechanism in macrophages. PLoS Biol. 2020 06; 18(6):e3000722. PMID: 32569301.
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    8. Cirovic B, de Bree LCJ, Groh L, Blok BA, Chan J, van der Velden WJFM, Bremmers MEJ, van Crevel R, Händler K, Picelli S, Schulte-Schrepping J, Klee K, Oosting M, Koeken VACM, van Ingen J, Li Y, Benn CS, Schultze JL, Joosten LAB, Curtis N, Netea MG, Schlitzer A. BCG Vaccination in Humans Elicits Trained Immunity via the Hematopoietic Progenitor Compartment. . 2020 08 12; 28(2):322-334.e5. PMID: 32544459.
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    9. Fischer-Riepe L, Daber N, Schulte-Schrepping J, Véras De Carvalho BC, Russo A, Pohlen M, Fischer J, Chasan AI, Wolf M, Ulas T, Glander S, Schulz C, Skryabin B, Wollbrink Dipl-Ing A, Steingraeber N, Stremmel C, Koehle M, Gärtner F, Vettorazzi S, Holzinger D, Gross J, Rosenbauer F, Stoll M, Niemann S, Tuckermann J, Schultze JL, Roth J, Barczyk-Kahlert K. CD163 expression defines specific, IRF8-dependent, immune-modulatory macrophages in the bone marrow. J Allergy Clin Immunol. 2020 Mar 19. PMID: 32199911.
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    10. Georganaki M, Ramachandran M, Tuit S, Núñez NG, Karampatzakis A, Fotaki G, van Hooren L, Huang H, Lugano R, Ulas T, Kaunisto A, Holland EC, Ellmark P, Mangsbo SM, Schultze J, Essand M, Tugues S, Dimberg A. Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy. Oncoimmunology. 2020; 9(1):1730538. PMID: 32231867.
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    11. Netea MG, Domínguez-Andrés J, Barreiro LB, Chavakis T, Divangahi M, Fuchs E, Joosten LAB, van der Meer JWM, Mhlanga MM, Mulder WJM, Riksen NP, Schlitzer A, Schultze JL, Stabell Benn C, Sun JC, Xavier RJ, Latz E. Defining trained immunity and its role in health and disease. Nat Rev Immunol. 2020 Jun; 20(6):375-388. PMID: 32132681.
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    12. Werner Y, Mass E, Ashok Kumar P, Ulas T, Händler K, Horne A, Klee K, Lupp A, Schütz D, Saaber F, Redecker C, Schultze JL, Geissmann F, Stumm R. Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke. Nat Neurosci. 2020 03; 23(3):351-362. PMID: 32042176.
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    13. Liepelt A, Hohlstein P, Gussen H, Xue J, Aschenbrenner AC, Ulas T, Buendgens L, Warzecha KT, Bartneck M, Luedde T, Trautwein C, Schultze JL, Koch A, Tacke F. Differential Gene Expression in Circulating CD14+ Monocytes Indicates the Prognosis of Critically Ill Patients with Sepsis. J Clin Med. 2020 Jan 02; 9(1). PMID: 31906585.
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    14. Warnat-Herresthal S, Perrakis K, Taschler B, Becker M, Baßler K, Beyer M, Günther P, Schulte-Schrepping J, Seep L, Klee K, Ulas T, Haferlach T, Mukherjee S, Schultze JL. Scalable Prediction of Acute Myeloid Leukemia Using High-Dimensional Machine Learning and Blood Transcriptomics. iScience. 2020 Jan 24; 23(1):100780. PMID: 31918046.
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    15. Schultze JL. Specificity meets function. Nat Immunol. 2019 12; 20(12):1565-1567. PMID: 31745339.
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    16. Camell CD, Günther P, Lee A, Goldberg EL, Spadaro O, Youm YH, Bartke A, Hubbard GB, Ikeno Y, Ruddle NH, Schultze J, Dixit VD. Aging Induces an Nlrp3 Inflammasome-Dependent Expansion of Adipose B Cells That Impairs Metabolic Homeostasis. Cell Metab. 2019 12 03; 30(6):1024-1039.e6. PMID: 31735593.
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    17. Tuit S, Salvagno C, Kapellos TS, Hau CS, Seep L, Oestreich M, Klee K, de Visser KE, Ulas T, Schultze JL. Transcriptional Signature Derived from Murine Tumor-Associated Macrophages Correlates with Poor Outcome in Breast Cancer Patients. Cell Rep. 2019 10 29; 29(5):1221-1235.e5. PMID: 31665635.
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    18. Günther P, Schultze JL. Mind the Map: Technology Shapes the Myeloid Cell Space. Front Immunol. 2019; 10:2287. PMID: 31636632.
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    19. Kapellos TS, Bonaguro L, Gemünd I, Reusch N, Saglam A, Hinkley ER, Schultze JL. Human Monocyte Subsets and Phenotypes in Major Chronic Inflammatory Diseases. Front Immunol. 2019; 10:2035. PMID: 31543877.
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    20. Placek K, Schultze JL, Aschenbrenner AC. Epigenetic reprogramming of immune cells in injury, repair, and resolution. J Clin Invest. 2019 07 22; 129(8):2994-3005. PMID: 31329166.
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    21. Sundararajan Z, Knoll R, Hombach P, Becker M, Schultze JL, Ulas T. Shiny-Seq: advanced guided transcriptome analysis. BMC Res Notes. 2019 Jul 18; 12(1):432. PMID: 31319888.
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    22. Sloot YJE, Rabold K, Ulas T, De Graaf DM, Heinhuis B, Händler K, Schultze JL, Netea MG, Smit JWA, Joosten LAB, Netea-Maier RT. Interplay between thyroid cancer cells and macrophages: effects on IL-32 mediated cell death and thyroid cancer cell migration. Cell Oncol (Dordr). 2019 Oct; 42(5):691-703. PMID: 31201646.
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    23. Placek K, Schultze JL, Netea MG. Immune memory characteristics of innate lymphoid cells. Curr Opin Infect Dis. 2019 06; 32(3):196-203. PMID: 31021952.
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    24. Schmidleithner L, Thabet Y, Schönfeld E, Köhne M, Sommer D, Abdullah Z, Sadlon T, Osei-Sarpong C, Subbaramaiah K, Copperi F, Haendler K, Varga T, Schanz O, Bourry S, Bassler K, Krebs W, Peters AE, Baumgart AK, Schneeweiss M, Klee K, Schmidt SV, Nüssing S, Sander J, Ohkura N, Waha A, Sparwasser T, Wunderlich FT, Förster I, Ulas T, Weighardt H, Sakaguchi S, Pfeifer A, Blüher M, Dannenberg AJ, Ferreirós N, Muglia LJ, Wickenhauser C, Barry SC, Schultze JL, Beyer M. Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction. Immunity. 2019 05 21; 50(5):1232-1248.e14. PMID: 31027998.
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    25. Goossens P, Rodriguez-Vita J, Etzerodt A, Masse M, Rastoin O, Gouirand V, Ulas T, Papantonopoulou O, Van Eck M, Auphan-Anezin N, Bebien M, Verthuy C, Vu Manh TP, Turner M, Dalod M, Schultze JL, Lawrence T. Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression. Cell Metab. 2019 06 04; 29(6):1376-1389.e4. PMID: 30930171.
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    26. Civit L, Theodorou I, Frey F, Weber H, Lingnau A, Gröber C, Blank M, Dambrune C, Stunden J, Beyer M, Schultze J, Latz E, Ducongé F, Kubbutat MHG, Mayer G. Targeting hormone refractory prostate cancer by in vivo selected DNA libraries in an orthotopic xenograft mouse model. Sci Rep. 2019 03 21; 9(1):4976. PMID: 30899039.
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    27. Salvagno C, Ciampricotti M, Tuit S, Hau CS, van Weverwijk A, Coffelt SB, Kersten K, Vrijland K, Kos K, Ulas T, Song JY, Ooi CH, Rüttinger D, Cassier PA, Jonkers J, Schultze JL, Ries CH, de Visser KE. Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response. Nat Cell Biol. 2019 04; 21(4):511-521. PMID: 30886344.
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    28. van der Poel M, Ulas T, Mizee MR, Hsiao CC, Miedema SSM, Schuurman KG, Helder B, Tas SW, Schultze JL, Hamann J, Huitinga I. Transcriptional profiling of human microglia reveals grey-white matter heterogeneity and multiple sclerosis-associated changes. Nat Commun. 2019 03 13; 10(1):1139. PMID: 30867424.
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    29. Schultze JL, Mass E, Schlitzer A. Emerging Principles in Myelopoiesis at Homeostasis and during Infection and Inflammation. Immunity. 2019 02 19; 50(2):288-301. PMID: 30784577.
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    30. Zwick M, Ulas T, Cho YL, Ried C, Grosse L, Simon C, Bernhard C, Busch DH, Schultze JL, Buchholz VR, Stutte S, Brocker T. Expression of the Phosphatase Ppef2 Controls Survival and Function of CD8+ Dendritic Cells. Front Immunol. 2019; 10:222. PMID: 30809231.
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    31. Bassler K, Schulte-Schrepping J, Warnat-Herresthal S, Aschenbrenner AC, Schultze JL. The Myeloid Cell Compartment-Cell by Cell. Annu Rev Immunol. 2019 04 26; 37:269-293. PMID: 30649988.
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    32. Netea MG, Schlitzer A, Placek K, Joosten LAB, Schultze JL. Innate and Adaptive Immune Memory: an Evolutionary Continuum in the Host's Response to Pathogens. . 2019 01 09; 25(1):13-26. PMID: 30629914.
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    33. Schultze JL. Myocardial infarction cell by cell. Nat Immunol. 2019 01; 20(1):7-9. PMID: 30538327.
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    34. Rakers C, Schleif M, Blank N, Matušková H, Ulas T, Händler K, Torres SV, Schumacher T, Tai K, Schultze JL, Jackson WS, Petzold GC. Stroke target identification guided by astrocyte transcriptome analysis. Glia. 2019 04; 67(4):619-633. PMID: 30585358.
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    35. Kabrani E, Chu VT, Tasouri E, Sommermann T, Baßler K, Ulas T, Zenz T, Bullinger L, Schultze JL, Rajewsky K, Sander S. Nuclear FOXO1 promotes lymphomagenesis in germinal center B cells. Blood. 2018 12 20; 132(25):2670-2683. PMID: 30333121.
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    36. Ravussin A, Youm YH, Sander J, Ryu S, Nguyen K, Varela L, Shulman GI, Sidorov S, Horvath TL, Schultze JL, Dixit VD. Loss of Nucleobindin-2 Causes Insulin Resistance in Obesity without Impacting Satiety or Adiposity. Cell Rep. 2018 07 31; 24(5):1085-1092.e6. PMID: 30067966.
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    37. Pfeiffer F, Gröber C, Blank M, Händler K, Beyer M, Schultze JL, Mayer G. Systematic evaluation of error rates and causes in short samples in next-generation sequencing. Sci Rep. 2018 Jul 19; 8(1):10950. PMID: 30026539.
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    38. Doebbeler M, Koenig C, Krzyzak L, Seitz C, Wild A, Ulas T, Baßler K, Kopelyanskiy D, Butterhof A, Kuhnt C, Kreiser S, Stich L, Zinser E, Knippertz I, Wirtz S, Riegel C, Hoffmann P, Edinger M, Nitschke L, Winkler T, Schultze JL, Steinkasserer A, Lechmann M. CD83 expression is essential for Treg cell differentiation and stability. JCI Insight. 2018 06 07; 3(11). PMID: 29875316.
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    39. Schultze JL, Rosenstiel P. Systems Medicine in Chronic Inflammatory Diseases. Immunity. 2018 04 17; 48(4):608-613. PMID: 29669240.
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    40. Pan WH, Sommer F, Falk-Paulsen M, Ulas T, Best P, Fazio A, Kachroo P, Luzius A, Jentzsch M, Rehman A, Müller F, Lengauer T, Walter J, Künzel S, Baines JF, Schreiber S, Franke A, Schultze JL, Bäckhed F, Rosenstiel P. Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development. Genome Med. 2018 04 13; 10(1):27. PMID: 29653584.
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    41. Wendeln AC, Degenhardt K, Kaurani L, Gertig M, Ulas T, Jain G, Wagner J, Häsler LM, Wild K, Skodras A, Blank T, Staszewski O, Datta M, Centeno TP, Capece V, Islam MR, Kerimoglu C, Staufenbiel M, Schultze JL, Beyer M, Prinz M, Jucker M, Fischer A, Neher JJ. Innate immune memory in the brain shapes neurological disease hallmarks. Nature. 2018 04; 556(7701):332-338. PMID: 29643512.
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    42. Bickert A, Kern P, van Uelft M, Herresthal S, Ulas T, Gutbrod K, Breiden B, Degen J, Sandhoff K, Schultze JL, Dörmann P, Hartmann D, Bauer R, Willecke K. Inactivation of ceramide synthase 2 catalytic activity in mice affects transcription of genes involved in lipid metabolism and cell division. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 07; 1863(7):734-749. PMID: 29653252.
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    43. Vogl T, Stratis A, Wixler V, Völler T, Thurainayagam S, Jorch SK, Zenker S, Dreiling A, Chakraborty D, Fröhling M, Paruzel P, Wehmeyer C, Hermann S, Papantonopoulou O, Geyer C, Loser K, Schäfers M, Ludwig S, Stoll M, Leanderson T, Schultze JL, König S, Pap T, Roth J. Autoinhibitory regulation of S100A8/S100A9 alarmin activity locally restricts sterile inflammation. J Clin Invest. 2018 05 01; 128(5):1852-1866. PMID: 29611822.
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    44. Schultze JL, Aschenbrenner AC. Systems immunology allows a new view on human dendritic cells. Semin Cell Dev Biol. 2019 02; 86:15-23. PMID: 29448068.
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    45. Kapellos TS, Bassler K, Aschenbrenner AC, Fujii W, Schultze JL. Dysregulated Functions of Lung Macrophage Populations in COPD. J Immunol Res. 2018; 2018:2349045. PMID: 29670919.
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    46. Gulei D, Irimie AI, Cojocneanu-Petric R, Schultze JL, Berindan-Neagoe I. Exosomes-Small Players, Big Sound. Bioconjug Chem. 2018 03 21; 29(3):635-648. PMID: 29369619.
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    47. Sociale M, Wulf AL, Breiden B, Klee K, Thielisch M, Eckardt F, Sellin J, Bülow MH, Löbbert S, Weinstock N, Voelzmann A, Schultze J, Sandhoff K, Bauer R. Ceramide Synthase Schlank Is a Transcriptional Regulator Adapting Gene Expression to Energy Requirements. Cell Rep. 2018 01 23; 22(4):967-978. PMID: 29386138.
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    48. Mitroulis I, Ruppova K, Wang B, Chen LS, Grzybek M, Grinenko T, Eugster A, Troullinaki M, Palladini A, Kourtzelis I, Chatzigeorgiou A, Schlitzer A, Beyer M, Joosten LAB, Isermann B, Lesche M, Petzold A, Simons K, Henry I, Dahl A, Schultze JL, Wielockx B, Zamboni N, Mirtschink P, Coskun Ü, Hajishengallis G, Netea MG, Chavakis T. Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity. Cell. 2018 01 11; 172(1-2):147-161.e12. PMID: 29328910.
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    49. Christ A, Günther P, Lauterbach MAR, Duewell P, Biswas D, Pelka K, Scholz CJ, Oosting M, Haendler K, Baßler K, Klee K, Schulte-Schrepping J, Ulas T, Moorlag SJCFM, Kumar V, Park MH, Joosten LAB, Groh LA, Riksen NP, Espevik T, Schlitzer A, Li Y, Fitzgerald ML, Netea MG, Schultze JL, Latz E. Western Diet Triggers NLRP3-Dependent Innate Immune Reprogramming. Cell. 2018 01 11; 172(1-2):162-175.e14. PMID: 29328911.
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    50. Ulas T, Schultze JL, Beyer M. Bioinformatic Assessment of Macrophage Activation by the Innate Immune System. Methods Mol Biol. 2018; 1714:19-40. PMID: 29177853.
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    51. Thion MS, Low D, Silvin A, Chen J, Grisel P, Schulte-Schrepping J, Blecher R, Ulas T, Squarzoni P, Hoeffel G, Coulpier F, Siopi E, David FS, Scholz C, Shihui F, Lum J, Amoyo AA, Larbi A, Poidinger M, Buttgereit A, Lledo PM, Greter M, Chan JKY, Amit I, Beyer M, Schultze JL, Schlitzer A, Pettersson S, Ginhoux F, Garel S. Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner. Cell. 2018 01 25; 172(3):500-516.e16. PMID: 29275859.
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    52. Sander J, Schmidt SV, Cirovic B, McGovern N, Papantonopoulou O, Hardt AL, Aschenbrenner AC, Kreer C, Quast T, Xu AM, Schmidleithner LM, Theis H, Thi Huong LD, Sumatoh HRB, Lauterbach MAR, Schulte-Schrepping J, Günther P, Xue J, Baßler K, Ulas T, Klee K, Katzmarski N, Herresthal S, Krebs W, Martin B, Latz E, Händler K, Kraut M, Kolanus W, Beyer M, Falk CS, Wiegmann B, Burgdorf S, Melosh NA, Newell EW, Ginhoux F, Schlitzer A, Schultze JL. Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2. Immunity. 2017 12 19; 47(6):1051-1066.e12. PMID: 29262348.
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    53. Wischhof L, Maida S, Piazzesi A, Gioran A, Barragan Sanz K, Irsen S, Beyer M, Schultze JL, Dyer MJ, Salomoni P, Ehninger D, Nicotera P, Bano D. The SWI/SNF subunit Bcl7a contributes to motor coordination and Purkinje cell function. Sci Rep. 2017 12 06; 7(1):17055. PMID: 29213114.
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    54. Civit L, Taghdisi SM, Jonczyk A, Haßel SK, Gröber C, Blank M, Stunden HJ, Beyer M, Schultze J, Latz E, Mayer G. Systematic evaluation of cell-SELEX enriched aptamers binding to breast cancer cells. Biochimie. 2018 Feb; 145:53-62. PMID: 29054799.
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    55. Fülle L, Steiner N, Funke M, Gondorf F, Pfeiffer F, Siegl J, Opitz FV, Haßel SK, Erazo AB, Schanz O, Stunden HJ, Blank M, Gröber C, Händler K, Beyer M, Weighardt H, Latz E, Schultze JL, Mayer G, Förster I. RNA Aptamers Recognizing Murine CCL17 Inhibit T Cell Chemotaxis and Reduce Contact Hypersensitivity In Vivo. Mol Ther. 2018 01 03; 26(1):95-104. PMID: 29103909.
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    56. Camell CD, Sander J, Spadaro O, Lee A, Nguyen KY, Wing A, Goldberg EL, Youm YH, Brown CW, Elsworth J, Rodeheffer MS, Schultze JL, Dixit VD. Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis during ageing. Nature. 2017 10 05; 550(7674):119-123. PMID: 28953873.
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    57. Ulas T, Pirr S, Fehlhaber B, Bickes MS, Loof TG, Vogl T, Mellinger L, Heinemann AS, Burgmann J, Schöning J, Schreek S, Pfeifer S, Reuner F, Völlger L, Stanulla M, von Köckritz-Blickwede M, Glander S, Barczyk-Kahlert K, von Kaisenberg CS, Friesenhagen J, Fischer-Riepe L, Zenker S, Schultze JL, Roth J, Viemann D. Corrigendum: S100-alarmin-induced innate immune programming protects newborn infants from sepsis. Nat Immunol. 2017 09 19; 18(10):1173. PMID: 28926540.
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    58. Hösel M, Quasdorff M, Ringelhan M, Kashkar H, Debey-Pascher S, Sprinzl MF, Bockmann JH, Arzberger S, Webb D, von Olshausen G, Weber A, Schultze JL, Büning H, Heikenwalder M, Protzer U. Hepatitis B Virus Activates Signal Transducer and Activator of Transcription 3 Supporting Hepatocyte Survival and Virus Replication. Cell Mol Gastroenterol Hepatol. 2017 Nov; 4(3):339-363. PMID: 28884137.
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    59. Aschenbrenner AC, Bassler K, Brondolin M, Bonaguro L, Carrera P, Klee K, Ulas T, Schultze JL, Hoch M. A cross-species approach to identify transcriptional regulators exemplified for Dnajc22 and Hnf4a. Sci Rep. 2017 06 22; 7(1):4056. PMID: 28642491.
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    60. Bilkei-Gorzo A, Albayram O, Draffehn A, Michel K, Piyanova A, Oppenheimer H, Dvir-Ginzberg M, Rácz I, Ulas T, Imbeault S, Bab I, Schultze JL, Zimmer A. A chronic low dose of ?9-tetrahydrocannabinol (THC) restores cognitive function in old mice. Nat Med. 2017 Jun; 23(6):782-787. PMID: 28481360.
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    61. See P, Dutertre CA, Chen J, Günther P, McGovern N, Irac SE, Gunawan M, Beyer M, Händler K, Duan K, Sumatoh HRB, Ruffin N, Jouve M, Gea-Mallorquí E, Hennekam RCM, Lim T, Yip CC, Wen M, Malleret B, Low I, Shadan NB, Fen CFS, Tay A, Lum J, Zolezzi F, Larbi A, Poidinger M, Chan JKY, Chen Q, Rénia L, Haniffa M, Benaroch P, Schlitzer A, Schultze JL, Newell EW, Ginhoux F. Mapping the human DC lineage through the integration of high-dimensional techniques. Science. 2017 06 09; 356(6342). PMID: 28473638.
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    62. Ulas T, Pirr S, Fehlhaber B, Bickes MS, Loof TG, Vogl T, Mellinger L, Heinemann AS, Burgmann J, Schöning J, Schreek S, Pfeifer S, Reuner F, Völlger L, Stanulla M, von Köckritz-Blickwede M, Glander S, Barczyk-Kahlert K, von Kaisenberg CS, Friesenhagen J, Fischer-Riepe L, Zenker S, Schultze JL, Roth J, Viemann D. S100-alarmin-induced innate immune programming protects newborn infants from sepsis. Nat Immunol. 2017 06; 18(6):622-632. PMID: 28459433.
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    63. Sander J, Schultze JL, Yosef N. ImpulseDE: detection of differentially expressed genes in time series data using impulse models. Bioinformatics. 2017 03 01; 33(5):757-759. PMID: 27797772.
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    64. Heine A, Held SAE, Schulte-Schrepping J, Wolff JFA, Klee K, Ulas T, Schmacke NA, Daecke SN, Riethausen K, Schultze JL, Brossart P. Generation and functional characterization of MDSC-like cells. Oncoimmunology. 2017; 6(4):e1295203. PMID: 28507805.
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    65. Aschenbrenner AC, Schultze JL. New "programmers" in tissue macrophage activation. Pflugers Arch. 2017 04; 469(3-4):375-383. PMID: 28185067.
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    66. Heidkamp GF, Sander J, Lehmann CHK, Heger L, Eissing N, Baranska A, Lühr JJ, Hoffmann A, Reimer KC, Lux A, Söder S, Hartmann A, Zenk J, Ulas T, McGovern N, Alexiou C, Spriewald B, Mackensen A, Schuler G, Schauf B, Forster A, Repp R, Fasching PA, Purbojo A, Cesnjevar R, Ullrich E, Ginhoux F, Schlitzer A, Nimmerjahn F, Schultze JL, Dudziak D. Human lymphoid organ dendritic cell identity is predominantly dictated by ontogeny, not tissue microenvironment. Sci Immunol. 2016 Dec 16; 1(6). PMID: 28783692.
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    67. Durek P, Nordström K, Gasparoni G, Salhab A, Kressler C, de Almeida M, Bassler K, Ulas T, Schmidt F, Xiong J, Glažar P, Klironomos F, Sinha A, Kinkley S, Yang X, Arrigoni L, Amirabad AD, Ardakani FB, Feuerbach L, Gorka O, Ebert P, Müller F, Li N, Frischbutter S, Schlickeiser S, Cendon C, Fröhler S, Felder B, Gasparoni N, Imbusch CD, Hutter B, Zipprich G, Tauchmann Y, Reinke S, Wassilew G, Hoffmann U, Richter AS, Sieverling L, Chang HD, Syrbe U, Kalus U, Eils J, Brors B, Manke T, Ruland J, Lengauer T, Rajewsky N, Chen W, Dong J, Sawitzki B, Chung HR, Rosenstiel P, Schulz MH, Schultze JL, Radbruch A, Walter J, Hamann A, Polansky JK. Epigenomic Profiling of Human CD4+ T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development. Immunity. 2016 11 15; 45(5):1148-1161. PMID: 27851915.
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    68. Schultze JL. Chromatin Remodeling in Monocyte and Macrophage Activation. Adv Protein Chem Struct Biol. 2017; 106:1-15. PMID: 28057208.
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    69. Schlitzer A, Schultze JL. Tissue-resident macrophages - how to humanize our knowledge. Immunol Cell Biol. 2017 02; 95(2):173-177. PMID: 27752049.
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    70. Tedeschi A, Dupraz S, Laskowski CJ, Xue J, Ulas T, Beyer M, Schultze JL, Bradke F. The Calcium Channel Subunit Alpha2delta2 Suppresses Axon Regeneration in the Adult CNS. Neuron. 2016 Oct 19; 92(2):419-434. PMID: 27720483.
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    71. Arts RJ, Plantinga TS, Tuit S, Ulas T, Heinhuis B, Tesselaar M, Sloot Y, Adema GJ, Joosten LA, Smit JW, Netea MG, Schultze JL, Netea-Maier RT. Transcriptional and metabolic reprogramming induce an inflammatory phenotype in non-medullary thyroid carcinoma-induced macrophages. Oncoimmunology. 2016; 5(12):e1229725. PMID: 28123869.
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    72. Schuette V, Embgenbroich M, Ulas T, Welz M, Schulte-Schrepping J, Draffehn AM, Quast T, Koch K, Nehring M, König J, Zweynert A, Harms FL, Steiner N, Limmer A, Förster I, Berberich-Siebelt F, Knolle PA, Wohlleber D, Kolanus W, Beyer M, Schultze JL, Burgdorf S. Mannose receptor induces T-cell tolerance via inhibition of CD45 and up-regulation of CTLA-4. Proc Natl Acad Sci U S A. 2016 09 20; 113(38):10649-54. PMID: 27601670.
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    73. Mass E, Ballesteros I, Farlik M, Halbritter F, Günther P, Crozet L, Jacome-Galarza CE, Händler K, Klughammer J, Kobayashi Y, Gomez-Perdiguero E, Schultze JL, Beyer M, Bock C, Geissmann F. Specification of tissue-resident macrophages during organogenesis. Science. 2016 09 09; 353(6304). PMID: 27492475.
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    74. Schultze JL. Macrophage tolerance in the gut: It is in the epigenome! Eur J Immunol. 2016 08; 46(8):1838-41. PMID: 27518699.
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    75. Szulzewsky F, Arora S, de Witte L, Ulas T, Markovic D, Schultze JL, Holland EC, Synowitz M, Wolf SA, Kettenmann H. Human glioblastoma-associated microglia/monocytes express a distinct RNA profile compared to human control and murine samples. Glia. 2016 08; 64(8):1416-36. PMID: 27312099.
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    76. Hackstein CP, Assmus LM, Welz M, Klein S, Schwandt T, Schultze J, Förster I, Gondorf F, Beyer M, Kroy D, Kurts C, Trebicka J, Kastenmüller W, Knolle PA, Abdullah Z. Gut microbial translocation corrupts myeloid cell function to control bacterial infection during liver cirrhosis. Gut. 2017 03; 66(3):507-518. PMID: 27432540.
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    77. Hagemeyer N, Kierdorf K, Frenzel K, Xue J, Ringelhan M, Abdullah Z, Godin I, Wieghofer P, Costa Jordão MJ, Ulas T, Yorgancioglu G, Rosenbauer F, Knolle PA, Heikenwalder M, Schultze JL, Prinz M. Transcriptome-based profiling of yolk sac-derived macrophages reveals a role for Irf8 in macrophage maturation. EMBO J. 2016 08 15; 35(16):1730-44. PMID: 27412700.
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    78. Brandstätter O, Schanz O, Vorac J, König J, Mori T, Maruyama T, Korkowski M, Haarmann-Stemmann T, von Smolinski D, Schultze JL, Abel J, Esser C, Takeyama H, Weighardt H, Förster I. Balancing intestinal and systemic inflammation through cell type-specific expression of the aryl hydrocarbon receptor repressor. Sci Rep. 2016 05 17; 6:26091. PMID: 27184933.
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    79. Zimmer S, Grebe A, Bakke SS, Bode N, Halvorsen B, Ulas T, Skjelland M, De Nardo D, Labzin LI, Kerksiek A, Hempel C, Heneka MT, Hawxhurst V, Fitzgerald ML, Trebicka J, Björkhem I, Gustafsson JÅ, Westerterp M, Tall AR, Wright SD, Espevik T, Schultze JL, Nickenig G, Lütjohann D, Latz E. Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming. Sci Transl Med. 2016 Apr 06; 8(333):333ra50. PMID: 27053774.
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    80. Schultze JL, Schmidt SV. Molecular features of macrophage activation. Semin Immunol. 2015 12; 27(6):416-23. PMID: 27049460.
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    81. Shahbazi E, Moradi S, Nemati S, Satarian L, Basiri M, Gourabi H, Zare Mehrjardi N, Günther P, Lampert A, Händler K, Hatay FF, Schmidt D, Molcanyi M, Hescheler J, Schultze JL, Saric T, Baharvand H. Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor. Stem Cell Reports. 2016 Apr 12; 6(4):539-551. PMID: 27052315.
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    82. Beins E, Ulas T, Ternes S, Neumann H, Schultze JL, Zimmer A. Characterization of inflammatory markers and transcriptome profiles of differentially activated embryonic stem cell-derived microglia. Glia. 2016 Jun; 64(6):1007-20. PMID: 26959607.
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    83. Beyer M, Abdullah Z, Chemnitz JM, Maisel D, Sander J, Lehmann C, Thabet Y, Shinde PV, Schmidleithner L, Köhne M, Trebicka J, Schierwagen R, Hofmann A, Popov A, Lang KS, Oxenius A, Buch T, Kurts C, Heikenwalder M, Fätkenheuer G, Lang PA, Hartmann P, Knolle PA, Schultze JL. Tumor-necrosis factor impairs CD4(+) T cell-mediated immunological control in chronic viral infection. Nat Immunol. 2016 May; 17(5):593-603. PMID: 26950238.
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    84. Deng M, Brägelmann J, Schultze JL, Perner S. Web-TCGA: an online platform for integrated analysis of molecular cancer data sets. BMC Bioinformatics. 2016 Feb 06; 17:72. PMID: 26852330.
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    85. Schultze JL, Beyer M. Myelopoiesis Reloaded: Single-Cell Transcriptomics Leads the Way. Immunity. 2016 Jan 19; 44(1):18-20. PMID: 26789920.
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    86. Schmidt SV, Krebs W, Ulas T, Xue J, Baßler K, Günther P, Hardt AL, Schultze H, Sander J, Klee K, Theis H, Kraut M, Beyer M, Schultze JL. The transcriptional regulator network of human inflammatory macrophages is defined by open chromatin. Cell Res. 2016 Feb; 26(2):151-70. PMID: 26729620.
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    87. Ginhoux F, Schultze JL, Murray PJ, Ochando J, Biswas SK. New insights into the multidimensional concept of macrophage ontogeny, activation and function. Nat Immunol. 2016 Jan; 17(1):34-40. PMID: 26681460.
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    88. Sorg UR, Behnke K, Degrandi D, Reich M, Keitel V, Herebian D, Deenen R, Beyer M, Schultze JL, Köhrer K, Gabbert HE, Mayatepek E, Häussinger D, Pfeffer K. Cooperative role of lymphotoxin ß receptor and tumor necrosis factor receptor p55 in murine liver regeneration. J Hepatol. 2016 May; 64(5):1108-1117. PMID: 26708145.
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    89. Milanez-Almeida P, Ulas T, Pasztoi M, Glage S, Schughart K, Lutz MB, Schultze JL, Huehn J. CD11b(+)Ly6C(++)Ly6G(-) Cells with Suppressive Activity Towards T Cells Accumulate in Lungs of Influenza a Virus-Infected Mice. Eur J Microbiol Immunol (Bp). 2015 Dec; 5(4):246-55. PMID: 26716013.
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    90. Vacchelli E, Ma Y, Baracco EE, Sistigu A, Enot DP, Pietrocola F, Yang H, Adjemian S, Chaba K, Semeraro M, Signore M, De Ninno A, Lucarini V, Peschiaroli F, Businaro L, Gerardino A, Manic G, Ulas T, Günther P, Schultze JL, Kepp O, Stoll G, Lefebvre C, Mulot C, Castoldi F, Rusakiewicz S, Ladoire S, Apetoh L, Bravo-San Pedro JM, Lucattelli M, Delarasse C, Boige V, Ducreux M, Delaloge S, Borg C, André F, Schiavoni G, Vitale I, Laurent-Puig P, Mattei F, Zitvogel L, Kroemer G. Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1. Science. 2015 Nov 20; 350(6263):972-8. PMID: 26516201.
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    91. Schultze JL. Reprogramming of macrophages--new opportunities for therapeutic targeting. Curr Opin Pharmacol. 2016 Feb; 26:10-5. PMID: 26426255.
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    92. Labzin LI, Schmidt SV, Masters SL, Beyer M, Krebs W, Klee K, Stahl R, Lütjohann D, Schultze JL, Latz E, De Nardo D. ATF3 Is a Key Regulator of Macrophage IFN Responses. J Immunol. 2015 Nov 01; 195(9):4446-55. PMID: 26416280.
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    93. Böttcher JP, Beyer M, Meissner F, Abdullah Z, Sander J, Höchst B, Eickhoff S, Rieckmann JC, Russo C, Bauer T, Flecken T, Giesen D, Engel D, Jung S, Busch DH, Protzer U, Thimme R, Mann M, Kurts C, Schultze JL, Kastenmüller W, Knolle PA. Functional classification of memory CD8(+) T cells by CX3CR1 expression. Nat Commun. 2015 Sep 25; 6:8306. PMID: 26404698.
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    94. Schultze JL. Teaching 'big data' analysis to young immunologists. Nat Immunol. 2015 Sep; 16(9):902-5. PMID: 26287590.
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    95. Schultze JL, Schmieder A, Goerdt S. Macrophage activation in human diseases. Semin Immunol. 2015 Aug; 27(4):249-56. PMID: 26303100.
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    96. Mitschka S, Ulas T, Goller T, Schneider K, Egert A, Mertens J, Brüstle O, Schorle H, Beyer M, Klee K, Xue J, Günther P, Bassler K, Schultze JL, Kolanus W. Co-existence of intact stemness and priming of neural differentiation programs in mES cells lacking Trim71. Sci Rep. 2015 Jun 09; 5:11126. PMID: 26057209.
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    97. Schultze JL. Transcriptional programming of human macrophages: on the way to systems immunology. J Mol Med (Berl). 2015 Jun; 93(6):589-97. PMID: 25877862.
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    98. Schultze JL, Freeman T, Hume DA, Latz E. A transcriptional perspective on human macrophage biology. Semin Immunol. 2015 Feb; 27(1):44-50. PMID: 25843246.
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    99. Sommer D, Peters AE, Wirtz T, Mai M, Ackermann J, Thabet Y, Schmidt J, Weighardt H, Wunderlich FT, Degen J, Schultze JL, Beyer M. Corrigendum: Efficient genome engineering by targeted homologous recombination in mouse embryos using transcription activator-like effector nucleases. Nat Commun. 2015 Feb 20; 6:5927. PMID: 25698449.
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    100. Schultze JL. Global transcriptional regulation in the immune system. Editorial. Semin Immunol. 2015 Feb; 27(1):1-3. PMID: 25926421.
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    101. Austermann J, Friesenhagen J, Fassl SK, Petersen B, Ortkras T, Burgmann J, Barczyk-Kahlert K, Faist E, Zedler S, Pirr S, Rohde C, Müller-Tidow C, von Köckritz-Blickwede M, von Kaisenberg CS, Flohé SB, Ulas T, Schultze JL, Roth J, Vogl T, Viemann D. Alarmins MRP8 and MRP14 induce stress tolerance in phagocytes under sterile inflammatory conditions. Cell Rep. 2014 Dec 24; 9(6):2112-23. PMID: 25497086.
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    102. Fassl SK, Austermann J, Papantonopoulou O, Riemenschneider M, Xue J, Bertheloot D, Freise N, Spiekermann C, Witten A, Viemann D, Kirschnek S, Stoll M, Latz E, Schultze JL, Roth J, Vogl T. Transcriptome assessment reveals a dominant role for TLR4 in the activation of human monocytes by the alarmin MRP8. J Immunol. 2015 Jan 15; 194(2):575-83. PMID: 25505274.
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    103. Krebs W, Schmidt SV, Goren A, De Nardo D, Labzin L, Bovier A, Ulas T, Theis H, Kraut M, Latz E, Beyer M, Schultze JL. Optimization of transcription factor binding map accuracy utilizing knockout-mouse models. Nucleic Acids Res. 2014 Dec 01; 42(21):13051-60. PMID: 25378309.
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    104. Sistigu A, Yamazaki T, Vacchelli E, Chaba K, Enot DP, Adam J, Vitale I, Goubar A, Baracco EE, Remédios C, Fend L, Hannani D, Aymeric L, Ma Y, Niso-Santano M, Kepp O, Schultze JL, Tüting T, Belardelli F, Bracci L, La Sorsa V, Ziccheddu G, Sestili P, Urbani F, Delorenzi M, Lacroix-Triki M, Quidville V, Conforti R, Spano JP, Pusztai L, Poirier-Colame V, Delaloge S, Penault-Llorca F, Ladoire S, Arnould L, Cyrta J, Dessoliers MC, Eggermont A, Bianchi ME, Pittet M, Engblom C, Pfirschke C, Préville X, Uzè G, Schreiber RD, Chow MT, Smyth MJ, Proietti E, André F, Kroemer G, Zitvogel L. Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy. Nat Med. 2014 Nov; 20(11):1301-9. PMID: 25344738.
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    105. Schmöle AC, Lundt R, Ternes S, Albayram Ö, Ulas T, Schultze JL, Bano D, Nicotera P, Alferink J, Zimmer A. Cannabinoid receptor 2 deficiency results in reduced neuroinflammation in an Alzheimer's disease mouse model. Neurobiol Aging. 2015 Feb; 36(2):710-9. PMID: 25443294.
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    106. Böttcher JP, Schanz O, Garbers C, Zaremba A, Hegenbarth S, Kurts C, Beyer M, Schultze JL, Kastenmüller W, Rose-John S, Knolle PA. IL-6 trans-signaling-dependent rapid development of cytotoxic CD8+ T cell function. Cell Rep. 2014 Sep 11; 8(5):1318-27. PMID: 25199826.
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    107. Schmidt SV, Schultze JL. New Insights into IDO Biology in Bacterial and Viral Infections. Front Immunol. 2014; 5:384. PMID: 25157255.
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    108. Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, Gordon S, Hamilton JA, Ivashkiv LB, Lawrence T, Locati M, Mantovani A, Martinez FO, Mege JL, Mosser DM, Natoli G, Saeij JP, Schultze JL, Shirey KA, Sica A, Suttles J, Udalova I, van Ginderachter JA, Vogel SN, Wynn TA. Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity. 2014 Jul 17; 41(1):14-20. PMID: 25035950.
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    109. Kummer MP, Hammerschmidt T, Martinez A, Terwel D, Eichele G, Witten A, Figura S, Stoll M, Schwartz S, Pape HC, Schultze JL, Weinshenker D, Heneka MT, Urban I. Ear2 deletion causes early memory and learning deficits in APP/PS1 mice. J Neurosci. 2014 Jun 25; 34(26):8845-54. PMID: 24966384.
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    110. Schultze JL. Precision attack on calcineurin in macrophages: a new anti-inflammatory weapon. EMBO J. 2014 May 16; 33(10):1087-8. PMID: 24674968.
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    111. Xue J, Schmidt SV, Sander J, Draffehn A, Krebs W, Quester I, De Nardo D, Gohel TD, Emde M, Schmidleithner L, Ganesan H, Nino-Castro A, Mallmann MR, Labzin L, Theis H, Kraut M, Beyer M, Latz E, Freeman TC, Ulas T, Schultze JL. Transcriptome-based network analysis reveals a spectrum model of human macrophage activation. Immunity. 2014 Feb 20; 40(2):274-88. PMID: 24530056.
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    112. Sommer D, Peters A, Wirtz T, Mai M, Ackermann J, Thabet Y, Schmidt J, Weighardt H, Wunderlich FT, Degen J, Schultze JL, Beyer M. Efficient genome engineering by targeted homologous recombination in mouse embryos using transcription activator-like effector nucleases. Nat Commun. 2014; 5:3045. PMID: 24413636.
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    113. Globisch T, Steiner N, Fülle L, Lukacs-Kornek V, Degrandi D, Dresing P, Alferink J, Lang R, Pfeffer K, Beyer M, Weighardt H, Kurts C, Ulas T, Schultze JL, Förster I. Cytokine-dependent regulation of dendritic cell differentiation in the splenic microenvironment. Eur J Immunol. 2014 Feb; 44(2):500-10. PMID: 24136200.
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    114. De Nardo D, Labzin LI, Kono H, Seki R, Schmidt SV, Beyer M, Xu D, Zimmer S, Lahrmann C, Schildberg FA, Vogelhuber J, Kraut M, Ulas T, Kerksiek A, Krebs W, Bode N, Grebe A, Fitzgerald ML, Hernandez NJ, Williams BR, Knolle P, Kneilling M, Röcken M, Lütjohann D, Wright SD, Schultze JL, Latz E. High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3. Nat Immunol. 2014 Feb; 15(2):152-60. PMID: 24317040.
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    115. Ma Y, Mattarollo SR, Adjemian S, Yang H, Aymeric L, Hannani D, Portela Catani JP, Duret H, Teng MW, Kepp O, Wang Y, Sistigu A, Schultze JL, Stoll G, Galluzzi L, Zitvogel L, Smyth MJ, Kroemer G. CCL2/CCR2-dependent recruitment of functional antigen-presenting cells into tumors upon chemotherapy. Cancer Res. 2014 Jan 15; 74(2):436-45. PMID: 24302580.
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    116. Lübkemeier I, Andrié R, Lickfett L, Bosen F, Stöckigt F, Dobrowolski R, Draffehn AM, Fregeac J, Schultze JL, Bukauskas FF, Schrickel JW, Willecke K. The Connexin40A96S mutation from a patient with atrial fibrillation causes decreased atrial conduction velocities and sustained episodes of induced atrial fibrillation in mice. J Mol Cell Cardiol. 2013 Dec; 65:19-32. PMID: 24060583.
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    117. Schermer B, Bartels V, Frommolt P, Habermann B, Braun F, Schultze JL, Roodbergen M, Hoeijmakers JH, Schumacher B, Nürnberg P, Dollé ME, Benzing T, Müller RU, Kurschat CE. Transcriptional profiling reveals progeroid Ercc1(-/?) mice as a model system for glomerular aging. BMC Genomics. 2013 Aug 16; 14:559. PMID: 23947592.
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    118. Niño-Castro A, Abdullah Z, Popov A, Thabet Y, Beyer M, Knolle P, Domann E, Chakraborty T, Schmidt SV, Schultze JL. The IDO1-induced kynurenines play a major role in the antimicrobial effect of human myeloid cells against Listeria monocytogenes. Innate Immun. 2014 May; 20(4):401-11. PMID: 23940074.
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    119. Beutner C, Linnartz-Gerlach B, Schmidt SV, Beyer M, Mallmann MR, Staratschek-Jox A, Schultze JL, Neumann H. Unique transcriptome signature of mouse microglia. Glia. 2013 Sep; 61(9):1429-42. PMID: 23832717.
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    120. Langhans B, Krämer B, Louis M, Nischalke HD, Hüneburg R, Staratschek-Jox A, Odenthal M, Manekeller S, Schepke M, Kalff J, Fischer HP, Schultze JL, Spengler U. Intrahepatic IL-8 producing Foxp3?CD4? regulatory T cells and fibrogenesis in chronic hepatitis C. J Hepatol. 2013 Aug; 59(2):229-35. PMID: 23624000.
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    121. Böttcher JP, Schanz O, Wohlleber D, Abdullah Z, Debey-Pascher S, Staratschek-Jox A, Höchst B, Hegenbarth S, Grell J, Limmer A, Atreya I, Neurath MF, Busch DH, Schmitt E, van Endert P, Kolanus W, Kurts C, Schultze JL, Diehl L, Knolle PA. Liver-primed memory T cells generated under noninflammatory conditions provide anti-infectious immunity. Cell Rep. 2013 Mar 28; 3(3):779-95. PMID: 23499443.
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    122. Jux B, Staratschek-Jox A, Penninger JM, Schultze JL, Kolanus W. Vav1 regulates MHCII expression in murine resting and activated B cells. Int Immunol. 2013 May; 25(5):307-17. PMID: 23391492.
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    123. Herzfeld T, Nolte D, Grznarova M, Hofmann A, Schultze JL, Müller U. X-linked dystonia parkinsonism syndrome (XDP, lubag): disease-specific sequence change DSC3 in TAF1/DYT3 affects genes in vesicular transport and dopamine metabolism. Hum Mol Genet. 2013 Mar 01; 22(5):941-51. PMID: 23184149.
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    124. Roth W, Kumar V, Beer HD, Richter M, Wohlenberg C, Reuter U, Thiering S, Staratschek-Jox A, Hofmann A, Kreusch F, Schultze JL, Vogl T, Roth J, Reichelt J, Hausser I, Magin TM. Keratin 1 maintains skin integrity and participates in an inflammatory network in skin through interleukin-18. J Cell Sci. 2012 Nov 15; 125(Pt 22):5269-79. PMID: 23132931.
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    125. Beyer M, Mallmann MR, Xue J, Staratschek-Jox A, Vorholt D, Krebs W, Sommer D, Sander J, Mertens C, Nino-Castro A, Schmidt SV, Schultze JL. High-resolution transcriptome of human macrophages. PLoS One. 2012; 7(9):e45466. PMID: 23029029.
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    126. Schmidt SV, Nino-Castro AC, Schultze JL. Regulatory dendritic cells: there is more than just immune activation. Front Immunol. 2012; 3:274. PMID: 22969767.
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    127. Hammerschmidt T, Kummer MP, Terwel D, Martinez A, Gorji A, Pape HC, Rommelfanger KS, Schroeder JP, Stoll M, Schultze J, Weinshenker D, Heneka MT. Selective loss of noradrenaline exacerbates early cognitive dysfunction and synaptic deficits in APP/PS1 mice. Biol Psychiatry. 2013 Mar 01; 73(5):454-63. PMID: 22883210.
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    128. Abdullah Z, Geiger S, Nino-Castro A, Böttcher JP, Muraliv E, Gaidt M, Schildberg FA, Riethausen K, Flossdorf J, Krebs W, Chakraborty T, Kurts C, Schultze JL, Knolle PA, Klotz L. Lack of PPAR? in myeloid cells confers resistance to Listeria monocytogenes infection. PLoS One. 2012; 7(5):e37349. PMID: 22629382.
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    129. Terme M, Ullrich E, Aymeric L, Meinhardt K, Coudert JD, Desbois M, Ghiringhelli F, Viaud S, Ryffel B, Yagita H, Chen L, Mécheri S, Kaplanski G, Prévost-Blondel A, Kato M, Schultze JL, Tartour E, Kroemer G, Degli-Esposti M, Chaput N, Zitvogel L. Cancer-induced immunosuppression: IL-18-elicited immunoablative NK cells. Cancer Res. 2012 Jun 01; 72(11):2757-67. PMID: 22427351.
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    130. Beyer M, Schumak B, Weihrauch MR, Andres B, Giese T, Endl E, Knolle PA, Classen S, Limmer A, Schultze JL. In vivo expansion of naïve CD4+ CD25(high) FOXP3+ regulatory T cells in patients with colorectal carcinoma after IL-2 administration. PLoS One. 2012; 7(1):e30422. PMID: 22276195.
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    131. Ihler F, Vetter EV, Pan J, Kammerer R, Debey-Pascher S, Schultze JL, Zimmermann W, Enders G. Expression of a neuroendocrine gene signature in gastric tumor cells from CEA 424-SV40 large T antigen-transgenic mice depends on SV40 large T antigen. PLoS One. 2012; 7(1):e29846. PMID: 22253802.
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    132. Schwandt T, Schumak B, Gielen GH, Jüngerkes F, Schmidbauer P, Klocke K, Staratschek-Jox A, van Rooijen N, Kraal G, Ludwig-Portugall I, Franken L, Wehner S, Kalff JC, Weber O, Kirschning C, Coch C, Kalinke U, Wenzel J, Kurts C, Zawatzky R, Holzmann B, Layland L, Schultze JL, Burgdorf S, den Haan JM, Knolle PA, Limmer A. Expression of type I interferon by splenic macrophages suppresses adaptive immunity during sepsis. EMBO J. 2012 Jan 04; 31(1):201-13. PMID: 22036947.
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    133. Beyer M, Classen S, Endl E, Kochanek M, Weihrauch MR, Debey-Pascher S, Knolle PA, Schultze JL. Comparative approach to define increased regulatory T cells in different cancer subtypes by combined assessment of CD127 and FOXP3. Clin Dev Immunol. 2011; 2011:734036. PMID: 21904560.
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    134. Beyer M, Thabet Y, Müller RU, Sadlon T, Classen S, Lahl K, Basu S, Zhou X, Bailey-Bucktrout SL, Krebs W, Schönfeld EA, Böttcher J, Golovina T, Mayer CT, Hofmann A, Sommer D, Debey-Pascher S, Endl E, Limmer A, Hippen KL, Blazar BR, Balderas R, Quast T, Waha A, Mayer G, Famulok M, Knolle PA, Wickenhauser C, Kolanus W, Schermer B, Bluestone JA, Barry SC, Sparwasser T, Riley JL, Schultze JL. Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation. Nat Immunol. 2011 Aug 14; 12(9):898-907. PMID: 21841785.
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    135. McInnes N, Sadlon TJ, Brown CY, Pederson S, Beyer M, Schultze JL, McColl S, Goodall GJ, Barry SC. FOXP3 and FOXP3-regulated microRNAs suppress SATB1 in breast cancer cells. Oncogene. 2012 Feb 23; 31(8):1045-54. PMID: 21743493.
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    136. Terme M, Ullrich E, Aymeric L, Meinhardt K, Desbois M, Delahaye N, Viaud S, Ryffel B, Yagita H, Kaplanski G, Prévost-Blondel A, Kato M, Schultze JL, Tartour E, Kroemer G, Chaput N, Zitvogel L. IL-18 induces PD-1-dependent immunosuppression in cancer. Cancer Res. 2011 Aug 15; 71(16):5393-9. PMID: 21724589.
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    137. Debey-Pascher S, Hofmann A, Kreusch F, Schuler G, Schuler-Thurner B, Schultze JL, Staratschek-Jox A. RNA-stabilized whole blood samples but not peripheral blood mononuclear cells can be stored for prolonged time periods prior to transcriptome analysis. J Mol Diagn. 2011 Jul; 13(4):452-60. PMID: 21704280.
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    138. Zander T, Hofmann A, Staratschek-Jox A, Classen S, Debey-Pascher S, Maisel D, Ansén S, Hahn M, Beyer M, Thomas RK, Gathof B, Mauch C, Delank KS, Engel-Riedel W, Wichmann HE, Stoelben E, Schultze JL, Wolf J. Blood-based gene expression signatures in non-small cell lung cancer. Clin Cancer Res. 2011 May 15; 17(10):3360-7. PMID: 21558400.
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    139. von Bubnoff D, Scheler M, Wilms H, Wenzel J, von Bubnoff N, Häcker G, Schultze J, Popov A, Racz P, Bieber T, Wickenhauser C. Indoleamine 2,3-dioxygenase-expressing myeloid dendritic cells and macrophages in infectious and noninfectious cutaneous granulomas. J Am Acad Dermatol. 2011 Oct; 65(4):819-832. PMID: 21501890.
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    140. Beyer M, Schultze JL. Plasticity of T(reg) cells: is reprogramming of T(reg) cells possible in the presence of FOXP3? Int Immunopharmacol. 2011 May; 11(5):555-60. PMID: 21115121.
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    141. Gupta MK, Illich DJ, Gaarz A, Matzkies M, Nguemo F, Pfannkuche K, Liang H, Classen S, Reppel M, Schultze JL, Hescheler J, Saric T. Global transcriptional profiles of beating clusters derived from human induced pluripotent stem cells and embryonic stem cells are highly similar. BMC Dev Biol. 2010 Sep 15; 10:98. PMID: 20843318.
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    142. Mallmann MR, Staratschek-Jox A, Rudlowski C, Braun M, Gaarz A, Wolfgarten M, Kuhn W, Schultze JL. Prediction and prognosis: impact of gene expression profiling in personalized treatment of breast cancer patients. EPMA J. 2010 Sep; 1(3):421-37. PMID: 23199086.
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    143. Kern M, Popov A, Kurts C, Schultze JL, Knolle PA. Taking off the brakes: T cell immunity in the liver. Trends Immunol. 2010 Aug; 31(8):311-7. PMID: 20619740.
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    144. Gaarz A, Debey-Pascher S, Classen S, Eggle D, Gathof B, Chen J, Fan JB, Voss T, Schultze JL, Staratschek-Jox A. Bead array-based microrna expression profiling of peripheral blood and the impact of different RNA isolation approaches. J Mol Diagn. 2010 May; 12(3):335-44. PMID: 20228267.
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    145. Classen S, Muth C, Debey-Pascher S, Eggle D, Beyer M, Mallmann MR, Rudlowski C, Zander T, Pölcher M, Kuhn W, Lahn M, Schultze JL, Staratschek-Jox A. Application of T cell-based transcriptomics to identify three candidate biomarkers for monitoring anti-TGFbetaR therapy. Pharmacogenet Genomics. 2010 Mar; 20(3):147-56. PMID: 20084050.
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    146. Staratschek-Jox A, Schultze JL. Re-overcoming barriers in translating biomarkers to clinical practice. Expert Opin Med Diagn. 2010 Mar; 4(2):103-12. PMID: 23484444.
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    147. Becker T, Loch G, Beyer M, Zinke I, Aschenbrenner AC, Carrera P, Inhester T, Schultze JL, Hoch M. FOXO-dependent regulation of innate immune homeostasis. Nature. 2010 Jan 21; 463(7279):369-73. PMID: 20090753.
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    148. Kondo E, Maecker B, Draube A, Klein-Gonzalez N, Shimabukuro-Vornhagen A, Schultze JL, von Bergwelt-Baildon MS. The shared tumor associated antigen cyclin-A2 is recognized by high-avidity T-cells. Int J Cancer. 2009 Nov 15; 125(10):2474-8. PMID: 19681121.
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    149. Klotz L, Burgdorf S, Dani I, Saijo K, Flossdorf J, Hucke S, Alferink J, Nowak N, Novak N, Beyer M, Mayer G, Langhans B, Klockgether T, Waisman A, Eberl G, Schultze J, Famulok M, Kolanus W, Glass C, Kurts C, Knolle PA. The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity. J Exp Med. 2009 Sep 28; 206(10):2079-89. PMID: 19737866.
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    150. Kern M, Popov A, Scholz K, Schumak B, Djandji D, Limmer A, Eggle D, Sacher T, Zawatzky R, Holtappels R, Reddehase MJ, Hartmann G, Debey-Pascher S, Diehl L, Kalinke U, Koszinowski U, Schultze J, Knolle PA. Virally infected mouse liver endothelial cells trigger CD8+ T-cell immunity. Gastroenterology. 2010 Jan; 138(1):336-46. PMID: 19737567.
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    151. Schurich A, Böttcher JP, Burgdorf S, Penzler P, Hegenbarth S, Kern M, Dolf A, Endl E, Schultze J, Wiertz E, Stabenow D, Kurts C, Knolle P. Distinct kinetics and dynamics of cross-presentation in liver sinusoidal endothelial cells compared to dendritic cells. Hepatology. 2009 Sep; 50(3):909-19. PMID: 19610048.
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    152. Pallasch CP, Patz M, Park YJ, Hagist S, Eggle D, Claus R, Debey-Pascher S, Schulz A, Frenzel LP, Claasen J, Kutsch N, Krause G, Mayr C, Rosenwald A, Plass C, Schultze JL, Hallek M, Wendtner CM. miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia. Blood. 2009 Oct 08; 114(15):3255-64. PMID: 19692702.
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    153. Terme M, Mignot G, Ullrich E, Bonmort M, Minard-Colin V, Jacquet A, Schultze JL, Kroemer G, Leclerc C, Chaput N, Zitvogel L. The dendritic cell-like functions of IFN-producing killer dendritic cells reside in the CD11b+ subset and are licensed by tumor cells. Cancer Res. 2009 Aug 15; 69(16):6590-7. PMID: 19679551.
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    154. Eggle D, Debey-Pascher S, Beyer M, Schultze JL. The development of a comparison approach for Illumina bead chips unravels unexpected challenges applying newest generation microarrays. BMC Bioinformatics. 2009 Jun 18; 10:186. PMID: 19538710.
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    155. Klotz L, Hucke S, Thimm D, Classen S, Gaarz A, Schultze J, Edenhofer F, Kurts C, Klockgether T, Limmer A, Knolle P, Burgdorf S. Increased antigen cross-presentation but impaired cross-priming after activation of peroxisome proliferator-activated receptor gamma is mediated by up-regulation of B7H1. J Immunol. 2009 Jul 01; 183(1):129-36. PMID: 19535643.
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    156. Beyer M, Karbach J, Mallmann MR, Zander T, Eggle D, Classen S, Debey-Pascher S, Famulok M, Jäger E, Schultze JL. Cancer vaccine enhanced, non-tumor-reactive CD8(+) T cells exhibit a distinct molecular program associated with "division arrest anergy". Cancer Res. 2009 May 15; 69(10):4346-54. PMID: 19435912.
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    157. Staratschek-Jox A, Classen S, Gaarz A, Debey-Pascher S, Schultze JL. Blood-based transcriptomics: leukemias and beyond. Expert Rev Mol Diagn. 2009 Apr; 9(3):271-80. PMID: 19379085.
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    158. Siebolts U, Breuhahn K, Hennecke A, Schultze JL, Wickenhauser C. Imbalance of DNA-dependent protein kinase subunits in polycythemia vera peripheral blood stem cells. Int J Cancer. 2009 Feb 01; 124(3):600-7. PMID: 19004005.
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    159. Kondo E, Gryschok L, Schultze JL, von Bergwelt-Baildon MS. Using CD40-activated B cells to efficiently identify epitopes of tumor antigens. J Immunother. 2009 Feb-Mar; 32(2):157-60. PMID: 19238014.
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    160. Beyer M, Schultze JL. Regulatory T cells: major players in the tumor microenvironment. Curr Pharm Des. 2009; 15(16):1879-92. PMID: 19519430.
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    161. Debey-Pascher S, Eggle D, Schultze JL. RNA stabilization of peripheral blood and profiling by bead chip analysis. Methods Mol Biol. 2009; 496:175-210. PMID: 18839112.
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    162. Kondo E, Maecker B, Weihrauch MR, Wickenhauser C, Zeng W, Nadler LM, Schultze JL, von Bergwelt-Baildon MS. Cyclin D1-specific cytotoxic T lymphocytes are present in the repertoire of cancer patients: implications for cancer immunotherapy. Clin Cancer Res. 2008 Oct 15; 14(20):6574-9. PMID: 18927298.
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    163. Popov A, Driesen J, Abdullah Z, Wickenhauser C, Beyer M, Debey-Pascher S, Saric T, Kummer S, Takikawa O, Domann E, Chakraborty T, Krönke M, Utermöhlen O, Schultze JL. Infection of myeloid dendritic cells with Listeria monocytogenes leads to the suppression of T cell function by multiple inhibitory mechanisms. J Immunol. 2008 Oct 01; 181(7):4976-88. PMID: 18802101.
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    164. Classen S, Staratschek-Jox A, Schultze JL. Use of genome-wide high-throughput technologies in biomarker development. Biomark Med. 2008 Oct; 2(5):509-24. PMID: 20477427.
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    165. Driesen J, Popov A, Schultze JL. CD25 as an immune regulatory molecule expressed on myeloid dendritic cells. Immunobiology. 2008; 213(9-10):849-58. PMID: 18926299.
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    166. Weihrauch MR, von Bergwelt-Baildon M, Kandic M, Weskott M, Klamp W, Rosler J, Schultze JL. T cell responses to hepatitis B surface antigen are detectable in non-vaccinated individuals. World J Gastroenterol. 2008 Apr 28; 14(16):2529-33. PMID: 18442200.
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    167. Beyer M, Schultze JL. Immunoregulatory T cells: role and potential as a target in malignancy. Curr Oncol Rep. 2008 Mar; 10(2):130-6. PMID: 18377826.
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    168. Pallasch CP, Schwamb J, Königs S, Schulz A, Debey S, Kofler D, Schultze JL, Hallek M, Ultsch A, Wendtner CM. Targeting lipid metabolism by the lipoprotein lipase inhibitor orlistat results in apoptosis of B-cell chronic lymphocytic leukemia cells. Leukemia. 2008 Mar; 22(3):585-92. PMID: 18079738.
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    169. Karbach J, Gnjatic S, Pauligk C, Bender A, Maeurer M, Schultze JL, Nadler K, Wahle C, Knuth A, Old LJ, Jäger E. Tumor-reactive CD8+ T-cell clones in patients after NY-ESO-1 peptide vaccination. Int J Cancer. 2007 Nov 01; 121(9):2042-8. PMID: 17640060.
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    170. Popov A, Schultze JL. IDO-expressing regulatory dendritic cells in cancer and chronic infection. J Mol Med (Berl). 2008 Feb; 86(2):145-60. PMID: 17876564.
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    171. Rebholz B, Haase I, Eckelt B, Paxian S, Flaig MJ, Ghoreschi K, Nedospasov SA, Mailhammer R, Debey-Pascher S, Schultze JL, Weindl G, Förster I, Huss R, Stratis A, Ruzicka T, Röcken M, Pfeffer K, Schmid RM, Rupec RA. Crosstalk between keratinocytes and adaptive immune cells in an IkappaBalpha protein-mediated inflammatory disease of the skin. Immunity. 2007 Aug; 27(2):296-307. PMID: 17692539.
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    172. Chemnitz JM, Eggle D, Driesen J, Classen S, Riley JL, Debey-Pascher S, Beyer M, Popov A, Zander T, Schultze JL. RNA fingerprints provide direct evidence for the inhibitory role of TGFbeta and PD-1 on CD4+ T cells in Hodgkin lymphoma. Blood. 2007 Nov 01; 110(9):3226-33. PMID: 17644739.
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    173. Beyer M, Schultze JL. CD4+CD25highFOXP3+ regulatory T cells in peripheral blood are primarily of effector memory phenotype. J Clin Oncol. 2007 Jun 20; 25(18):2628-30; author reply 2630-2. PMID: 17577047.
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    174. Classen S, Zander T, Eggle D, Chemnitz JM, Brors B, Büchmann I, Popov A, Beyer M, Eils R, Debey S, Schultze JL. Human resting CD4+ T cells are constitutively inhibited by TGF beta under steady-state conditions. J Immunol. 2007 Jun 01; 178(11):6931-40. PMID: 17513742.
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    175. Draube A, Beyer M, Schumer S, Thomas RK, von Tresckow B, Koslowsky TC, Krieglstein CF, Schultze JL, Wolf J. Efficient activation of autologous tumor-specific T cells: a simple coculture technique of autologous dendritic cells compared to established cell fusion strategies in primary human colorectal carcinoma. J Immunother. 2007 May-Jun; 30(4):359-69. PMID: 17457211.
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    176. Jensen M, Klehr M, Vogel A, Schmitz S, Tawadros S, Mühlenhoff M, Plück A, Fischer T, Schomäcker K, Schultze JL, Berthold F. One step generation of fully chimeric antibodies using Cgamma1- and Ckappa mutant mice. J Immunother. 2007 Apr; 30(3):338-49. PMID: 17414325.
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    177. Schultze JL, Eggle D. IlluminaGUI: graphical user interface for analyzing gene expression data generated on the Illumina platform. Bioinformatics. 2007 Jun 01; 23(11):1431-3. PMID: 17384020.
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    178. Popov A, Abdullah Z, Wickenhauser C, Saric T, Driesen J, Hanisch FG, Domann E, Raven EL, Dehus O, Hermann C, Eggle D, Debey S, Chakraborty T, Krönke M, Utermöhlen O, Schultze JL. Indoleamine 2,3-dioxygenase-expressing dendritic cells form suppurative granulomas following Listeria monocytogenes infection. J Clin Invest. 2006 Dec; 116(12):3160-70. PMID: 17111046.
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    179. Schmitz R, Thomas RK, Harttrampf AC, Wickenhauser C, Schultze JL, Hansmann ML, Wolf J, Küppers R. The major subtypes of human B-cell lymphomas lack mutations in BCL-2 family member BAD. Int J Cancer. 2006 Oct 01; 119(7):1738-40. PMID: 16646081.
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    180. Schultze JL. [Requirements for the development of molecularly defined targeted therapy in oncology]. Med Klin (Munich). 2006 Aug 15; 101(8):617-23. PMID: 16896568.
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    181. Beyer M, Schultze JL. Regulatory T cells in cancer. Blood. 2006 Aug 01; 108(3):804-11. PMID: 16861339.
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    182. Fiore F, Von Bergwelt-Baildon MS, Drebber U, Beyer M, Popov A, Manzke O, Wickenhauser C, Baldus SE, Schultze JL. Dendritic cells are significantly reduced in non-Hodgkin's lymphoma and express less CCR7 and CD62L. Leuk Lymphoma. 2006 Apr; 47(4):613-22. PMID: 16690519.
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    183. Kaderali L, Zander T, Faigle U, Wolf J, Schultze JL, Schrader R. CASPAR: a hierarchical bayesian approach to predict survival times in cancer from gene expression data. Bioinformatics. 2006 Jun 15; 22(12):1495-502. PMID: 16554338.
      Citations:    
    184. Bartsch M, Gobbato E, Bednarek P, Debey S, Schultze JL, Bautor J, Parker JE. Salicylic acid-independent ENHANCED DISEASE SUSCEPTIBILITY1 signaling in Arabidopsis immunity and cell death is regulated by the monooxygenase FMO1 and the Nudix hydrolase NUDT7. Plant Cell. 2006 Apr; 18(4):1038-51. PMID: 16531493.
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    185. von Bergwelt-Baildon MS, Popov A, Saric T, Chemnitz J, Classen S, Stoffel MS, Fiore F, Roth U, Beyer M, Debey S, Wickenhauser C, Hanisch FG, Schultze JL. CD25 and indoleamine 2,3-dioxygenase are up-regulated by prostaglandin E2 and expressed by tumor-associated dendritic cells in vivo: additional mechanisms of T-cell inhibition. Blood. 2006 Jul 01; 108(1):228-37. PMID: 16522817.
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    186. Chemnitz JM, Driesen J, Classen S, Riley JL, Debey S, Beyer M, Popov A, Zander T, Schultze JL. Prostaglandin E2 impairs CD4+ T cell activation by inhibition of lck: implications in Hodgkin's lymphoma. Cancer Res. 2006 Jan 15; 66(2):1114-22. PMID: 16424048.
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    187. Beyer M, Kochanek M, Giese T, Endl E, Weihrauch MR, Knolle PA, Classen S, Schultze JL. In vivo peripheral expansion of naive CD4+CD25high FoxP3+ regulatory T cells in patients with multiple myeloma. Blood. 2006 May 15; 107(10):3940-9. PMID: 16410445.
      Citations:    
    188. Debey S, Zander T, Brors B, Popov A, Eils R, Schultze JL. A highly standardized, robust, and cost-effective method for genome-wide transcriptome analysis of peripheral blood applicable to large-scale clinical trials. Genomics. 2006 May; 87(5):653-64. PMID: 16387473.
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    189. von Bergwelt-Baildon M, Shimabukuro-Vornhagen A, Popov A, Klein-Gonzalez N, Fiore F, Debey S, Draube A, Maecker B, Menezes I, Nadler LM, Schultze JL. CD40-activated B cells express full lymph node homing triad and induce T-cell chemotaxis: potential as cellular adjuvants. Blood. 2006 Apr 01; 107(7):2786-9. PMID: 16357329.
      Citations:    
    190. Thomas RK, Sos ML, Zander T, Mani O, Popov A, Berenbrinker D, Smola-Hess S, Schultze JL, Wolf J. Inhibition of nuclear translocation of nuclear factor-kappaB despite lack of functional IkappaBalpha protein overcomes multiple defects in apoptosis signaling in human B-cell malignancies. Clin Cancer Res. 2005 Nov 15; 11(22):8186-94. PMID: 16299251.
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    191. Maecker B, von Bergwelt-Baildon MS, Anderson KS, Vonderheide RH, Anderson KC, Nadler LM, Schultze JL. Rare naturally occurring immune responses to three epitopes from the widely expressed tumour antigens hTERT and CYP1B1 in multiple myeloma patients. Clin Exp Immunol. 2005 Sep; 141(3):558-62. PMID: 16045747.
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    192. Weihrauch MR, Manzke O, Beyer M, Haverkamp H, Diehl V, Bohlen H, Wolf J, Schultze JL. Elevated serum levels of CC thymus and activation-related chemokine (TARC) in primary Hodgkin's disease: potential for a prognostic factor. Cancer Res. 2005 Jul 01; 65(13):5516-9. PMID: 15994922.
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    193. Maecker B, von Bergwelt-Baildon MS, Sherr DH, Nadler LM, Schultze JL. Identification of a new HLA-A*0201-restricted cryptic epitope from CYP1B1. Int J Cancer. 2005 Jun 10; 115(2):333-6. PMID: 15688394.
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    194. Thomas RK, Schmitz R, Harttrampf AC, Abdil-Hadi A, Wickenhauser C, Distler V, Hansmann ML, Schultze JL, Küppers R, Wolf J. Apoptosis-resistant phenotype of classical Hodgkin's lymphoma is not mediated by somatic mutations within genes encoding members of the death-inducing signaling complex (DISC). Leukemia. 2005 Jun; 19(6):1079-82. PMID: 15815717.
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    195. Beyer M, Kochanek M, Darabi K, Popov A, Jensen M, Endl E, Knolle PA, Thomas RK, von Bergwelt-Baildon M, Debey S, Hallek M, Schultze JL. Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine. Blood. 2005 Sep 15; 106(6):2018-25. PMID: 15914560.
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    196. Both M, Schultze J, Reuter M, Bewig B, Hubner R, Bobis I, Noth R, Heller M, Biederer J. Fast T1- and T2-weighted pulmonary MR-imaging in patients with bronchial carcinoma. Eur J Radiol. 2005 Mar; 53(3):478-88. PMID: 15741023.
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    197. Schultze JL, Grabbe S, von Bergwelt-Baildon MS. DCs and CD40-activated B cells: current and future avenues to cellular cancer immunotherapy. Trends Immunol. 2004 Dec; 25(12):659-64. PMID: 15530836.
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    198. von Bergwelt-Baildon M, Maecker B, Schultze J, Gribben JG. CD40 activation: potential for specific immunotherapy in B-CLL. Ann Oncol. 2004 Jun; 15(6):853-7. PMID: 15151939.
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    199. von Bergwelt-Baildon M, Schultze JL, Maecker B, Menezes I, Nadler LM. Correspondence re R. Lapointe et al., CD40-stimulated B lymphocytes pulsed with tumor antigens are effective antigen-presenting cells that can generate specific T cells. Cancer Res 2003;63:2836-43. Cancer Res. 2004 Jun 01; 64(11):4055-6; author reply 4056-7. PMID: 15173021.
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    200. Wendt TG, Gademann G, Pambor C, Grießbach I, von Specht H, Martin T, Baltas D, Kurek R, Röddiger S, Tunn UW, Zamboglou N, Eich HT, Staar S, Gossmann A, Hansemann K, Semrau R, Skripnitchenko R, Diehl V, Müller RP, Sehlen S, Willich N, Rühl U, Lukas P, Dühmke E, Engel K, Tabbert E, Bolck M, Knaack S, Annweiler H, Krempien R, Hoppe H, Harms W, Daeuber S, Schorr O, Treiber M, Debus J, Alber M, Paulsen F, Birkner M, Bakai A, Belka C, Budach W, Grosser KH, Kramer R, Kober B, Reinert M, Schneider P, Hertel A, Feldmann H, Csere P, Hoinkis C, Rothe G, Zahn P, Alheit H, Cavanaugh SX, Kupelian P, Reddy C, Pollock B, Fuss M, Roeddiger S, Dannenberg T, Rogge B, Drechsler D, Herrmann T, Alberti W, Schwarz R, Graefen M, Krüll A, Rudat V, Huland H, Fehr C, Baum C, Glocker S, Nüsslin F, Heil T, Lemnitzer H, Knips M, Baumgart O, Thiem W, Kloetzer KH, Hoffmann L, Neu B, Hültenschmidt B, Sautter-Bihl ML, Micke O, Seegenschmiedt MH, Köppen D, Klautke G, Fietkau R, Schultze J, Schlichting G, Koltze H, Kimmig B, Glatzel M, Fröhlich D, Bäsecke S, Krauß A, Strauß D, Buth KJ, Böhme R, Oehler W, Bottke D, Keilholz U, Heufelder K, Wiegel T, Hinkelbein W, Rödel C, Papadopoulos T, Munnes M, Wirtz R, Sauer R, Rödel F, Lubgan D, Distel L, Grabenbauer GG, Sak A, Stüben G, Pöttgen C, Grehl S, Stuschke M, Müller K, Pfaffendorf C, Mayerhofer A, Köhn FM, Ring J, van Beuningen D, Meineke V, Neubauer S, Keller U, Wittlinger M, Riesenbeck D, Greve B, Exeler R, Ibrahim M, Liebscher C, Severin E, Ott O, Pötter R, Hammer J, Hildebrandt G, Beckmann MW, Strnad V, Fehlauer F, Tribius S, Bajrovic A, Höller U, Rades D, Warszawski A, Baumann R, Madry-Gevecke B, Karstens JH, Grehn C, Hensley F, Berns C, Wannenmacher M, Semrau S, Reimer T, Gerber B, Ketterer P, Koepcke E, Hänsgen G, Strauß HG, Dunst J, Füller J, Kalb S, Wendt T, Weitmann HD, Waldhäusl C, Knocke TH, Lamprecht U, Classen J, Kaulich TW, Aydeniz B, Bamberg M, Wiezorek T, Banz N, Salz H, Scheithauer M, Schwedas M, Lutterbach J, Bartelt S, Frommhold H, Lambert J, Hornung D, Swiderski S, Walke M, Siefert A, Pöllinger B, Krimmel K, Schaffer M, Koelbl O, Bratengeier K, Vordermark D, Flentje M, Hero B, Berthold F, Combs SE, Gutwein S, Schulz-Ertner D, van Kampen M, Thilmann C, Kocher M, Kunze S, Schild S, Ikezaki K, Müller B, Sieber R, Weiß C, Wolf I, Wenz F, Weber KJ, Schäfer J, Engling A, Laufs S, Veldwijk MR, Milanovic D, Fleckenstein K, Zeller W, Fruehauf S, Herskind C, Weinmann M, Jendrossek V, Rübe C, Appold S, Kusche S, Hölscher T, Brüchner K, Geyer P, Baumann M, Kumpf R, Zimmermann F, Schill S, Geinitz H, Nieder C, Jeremic B, Molls M, Liesenfeld S, Petrat H, Hesselmann S, Schäfer U, Bruns F, Horst E, Wilkowski R, Assmann G, Nolte A, Diebold J, Löhrs U, Fritz P, Hans-Jürgen K, Mühlnickel W, Bach P, Wahlers B, Kraus HJ, Wulf J, Hädinger U, Baier K, Krieger T, Müller G, Hof H, Herfarth K, Brunner T, Hahn SM, Schreiber FS, Rustgi AK, McKenna WG, Bernhard EJ, Guckenberger M, Meyer K, Willner J, Schmidt M, Kolb M, Li M, Gong P, Abdollahi A, Trinh T, Huber PE, Christiansen H, Saile B, Neubauer-Saile K, Tippelt S, Rave-Fränk M, Hermann RM, Dudas J, Hess CF, Schmidberger H, Ramadori G, Andratschke N, Price R, Ang KK, Schwarz S, Kulka U, Busch M, Schlenger L, Bohsung J, Eichwurzel I, Matnjani G, Sandrock D, Richter M, Wurm R, Budach V, Feussner A, Gellermann J, Jordan A, Scholz R, Gneveckow U, Maier-Hauff K, Ullrich R, Wust P, Felix R, Waldöfner N, Seebass M, Ochel HJ, Dani A, Varkonyi A, Osvath M, Szasz A, Messer PM, Blumstein NM, Gottfried HW, Schneider E, Reske SN, Röttinger EM, Grosu AL, Franz M, Stärk S, Weber W, Heintz M, Indenkämpen F, Beyer T, Lübcke W, Levegrün S, Hayen J, Czech N, Mbarek B, Köster R, Thurmann H, Todorovic M, Schuchert A, Meinertz T, Münzel T, Grundtke H, Hornig B, Hehr T, Dilcher C, Chan RC, Mintz GS, Kotani JI, Shah VM, Canos DA, Weissman NJ, Waksman R, Wolfram R, Bürger B, Schrappe M, Timmermann B, Lomax A, Goitein G, Schuck A, Mattke A, Int-Veen C, Brecht I, Bernhard S, Treuner J, et al. [Not Available]. Strahlenther Onkol. 2004 Jun; 180 Suppl 1:5-87. PMID: 27137922.
      Citations:    
    201. Jensen M, Tawadros S, Sedlacek HH, Schultze JL, Berthold F. NK cell depletion diminish tumour-specific B cell responses. Immunol Lett. 2004 May 15; 93(2-3):205-10. PMID: 15158618.
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    202. Vonderheide RH, Domchek SM, Schultze JL, George DJ, Hoar KM, Chen DY, Stephans KF, Masutomi K, Loda M, Xia Z, Anderson KS, Hahn WC, Nadler LM. Vaccination of cancer patients against telomerase induces functional antitumor CD8+ T lymphocytes. Clin Cancer Res. 2004 Feb 01; 10(3):828-39. PMID: 14871958.
      Citations:    
    203. Debey S, Schoenbeck U, Hellmich M, Gathof BS, Pillai R, Zander T, Schultze JL. Comparison of different isolation techniques prior gene expression profiling of blood derived cells: impact on physiological responses, on overall expression and the role of different cell types. Pharmacogenomics J. 2004; 4(3):193-207. PMID: 15037859.
      Citations:    
    204. Schultze JL, Fiore F, von Bergwelt-Baildon M. DCs in lymphoma--biology and therapeutic aspects. Cytotherapy. 2004; 6(2):138-47. PMID: 15203990.
      Citations:    
    205. Hanisch FG, Schwientek T, Von Bergwelt-Baildon MS, Schultze JL, Finn O. O-Linked glycans control glycoprotein processing by antigen-presenting cells: a biochemical approach to the molecular aspects of MUC1 processing by dendritic cells. Eur J Immunol. 2003 Dec; 33(12):3242-54. PMID: 14635032.
      Citations:    
    206. Jensen M, Ernestus K, Kemshead J, Klehr M, Von Bergwelt-Baildon MS, Schinköthe T, Schultze JL, Berthold F. The bi-specific CD3 x NCAM antibody: a model to preactivate T cells prior to tumour cell lysis. Clin Exp Immunol. 2003 Nov; 134(2):253-63. PMID: 14616785.
      Citations:    
    207. Hirano N, Butler MO, Von Bergwelt-Baildon MS, Maecker B, Schultze JL, O'Connor KC, Schur PH, Kojima S, Guinan EC, Nadler LM. Autoantibodies frequently detected in patients with aplastic anemia. Blood. 2003 Dec 15; 102(13):4567-75. PMID: 12947009.
      Citations:    
    208. Maecker B, Sherr DH, Vonderheide RH, von Bergwelt-Baildon MS, Hirano N, Anderson KS, Xia Z, Butler MO, Wucherpfennig KW, O'Hara C, Cole G, Kwak SS, Ramstedt U, Tomlinson AJ, Chicz RM, Nadler LM, Schultze JL. The shared tumor-associated antigen cytochrome P450 1B1 is recognized by specific cytotoxic T cells. Blood. 2003 Nov 01; 102(9):3287-94. PMID: 12869499.
      Citations:    
    209. Maecker B, Anderson KS, von Bergwelt-Baildon MS, Weller E, Vonderheide RH, Richardson PG, Schlossman RL, Menezes IA, Xia Z, Munshi NC, Anderson KC, Nadler LM, Schultze JL. Viral antigen-specific CD8+ T-cell responses are impaired in multiple myeloma. Br J Haematol. 2003 Jun; 121(6):842-8. PMID: 12786794.
      Citations:    
    210. Nolte A, Scheffold C, Slotty J, Huenefeld C, Schultze JL, Grabbe S, Berdel WE, Kienast J. Generation of melanoma-specific cytotoxic T lymphocytes for allogeneic immunotherapy. J Immunother. 2003 May-Jun; 26(3):257-69. PMID: 12806279.
      Citations:    
    211. Schmollinger JC, Vonderheide RH, Hoar KM, Maecker B, Schultze JL, Hodi FS, Soiffer RJ, Jung K, Kuroda MJ, Letvin NL, Greenfield EA, Mihm M, Kutok JL, Dranoff G. Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction. Proc Natl Acad Sci U S A. 2003 Mar 18; 100(6):3398-403. PMID: 12626761.
      Citations:    
    212. Nadler LM, Schultze JL. From genomics to cancer vaccines: patient-tailored or universal vaccines? Curr Opin Mol Ther. 2002 Dec; 4(6):572-6. PMID: 12596359.
      Citations:    
    213. Husson H, Freedman AS, Cardoso AA, Schultze J, Munoz O, Strola G, Kutok J, Carideo EG, De Beaumont R, Caligaris-Cappio F, Ghia P. CXCL13 (BCA-1) is produced by follicular lymphoma cells: role in the accumulation of malignant B cells. Br J Haematol. 2002 Nov; 119(2):492-5. PMID: 12406091.
      Citations:    
    214. Schultze JL. Degeneracy instead of specificity: is this a solution to cancer immunotherapy? Trends Immunol. 2002 Jul; 23(7):343-4; author reply 344-5. PMID: 12103351.
      Citations:    
    215. Scardino A, Gross DA, Alves P, Schultze JL, Graff-Dubois S, Faure O, Tourdot S, Chouaib S, Nadler LM, Lemonnier FA, Vonderheide RH, Cardoso AA, Kosmatopoulos K. HER-2/neu and hTERT cryptic epitopes as novel targets for broad spectrum tumor immunotherapy. J Immunol. 2002 Jun 01; 168(11):5900-6. PMID: 12023395.
      Citations:    
    216. von Bergwelt-Baildon MS, Vonderheide RH, Maecker B, Hirano N, Anderson KS, Butler MO, Xia Z, Zeng WY, Wucherpfennig KW, Nadler LM, Schultze JL. Human primary and memory cytotoxic T lymphocyte responses are efficiently induced by means of CD40-activated B cells as antigen-presenting cells: potential for clinical application. Blood. 2002 May 01; 99(9):3319-25. PMID: 11964299.
      Citations:    
    217. Thomas RK, Kallenborn A, Wickenhauser C, Schultze JL, Draube A, Vockerodt M, Re D, Diehl V, Wolf J. Constitutive expression of c-FLIP in Hodgkin and Reed-Sternberg cells. Am J Pathol. 2002 Apr; 160(4):1521-8. PMID: 11943736.
      Citations:    
    218. Schultze JL, Bohlen H. Influence of genomics on cancer vaccine development from guess to prediction. Curr Pharm Des. 2002; 8(19):1735-48. PMID: 12171545.
      Citations:    
    219. Husson H, Carideo EG, Neuberg D, Schultze J, Munoz O, Marks PW, Donovan JW, Chillemi AC, O'Connell P, Freedman AS. Gene expression profiling of follicular lymphoma and normal germinal center B cells using cDNA arrays. Blood. 2002 Jan 01; 99(1):282-9. PMID: 11756183.
      Citations:    
    220. Gitelson E, Spaner D, Buckstein R, Franssen E, Hewitt K, Lim MS, Pennell N, Schultze JL, Berinstein NL. T-cell analysis in identical twins reveals an impaired anti-follicular lymphoma immune response in the patient but not in the healthy twin. Br J Haematol. 2002 Jan; 116(1):122-7. PMID: 11841404.
      Citations:    
    221. Vonderheide RH, Schultze JL, Anderson KS, Maecker B, Butler MO, Xia Z, Kuroda MJ, von Bergwelt-Baildon MS, Bedor MM, Hoar KM, Schnipper DR, Brooks MW, Letvin NL, Stephans KF, Wucherpfennig KW, Hahn WC, Nadler LM. Equivalent induction of telomerase-specific cytotoxic T lymphocytes from tumor-bearing patients and healthy individuals. Cancer Res. 2001 Dec 01; 61(23):8366-70. PMID: 11731409.
      Citations:    
    222. Husson H, Carideo EG, Cardoso AA, Lugli SM, Neuberg D, Munoz O, de Leval L, Schultze J, Freedman AS. MCP-1 modulates chemotaxis by follicular lymphoma cells. Br J Haematol. 2001 Dec; 115(3):554-62. PMID: 11736935.
      Citations:    
    223. Maecker B, Anderson KS, Vonderheide RH, Schultze JL. Linking genomics to immunotherapy by reverse immunology--'immunomics' in the new millennium. Curr Mol Med. 2001 Nov; 1(5):609-19. PMID: 11899235.
      Citations:    
    224. Vonderheide RH, Anderson KS, Hahn WC, Butler MO, Schultze JL, Nadler LM. Characterization of HLA-A3-restricted cytotoxic T lymphocytes reactive against the widely expressed tumor antigen telomerase. Clin Cancer Res. 2001 Nov; 7(11):3343-8. PMID: 11705846.
      Citations:    
    225. Vonderheide RH, Butler MO, Liu JF, Battle TE, Hirano N, Gribben JG, Frank DA, Schultze JL, Nadler LM. CD40 activation of carcinoma cells increases expression of adhesion and major histocompatibility molecules but fails to induce either CD80/CD86 expression or T cell alloreactivity. Int J Oncol. 2001 Oct; 19(4):791-8. PMID: 11562757.
      Citations:    
    226. Koch P, del Valle F, Berdel WE, Willich NA, Reers B, Hiddemann W, Grothaus-Pinke B, Reinartz G, Brockmann J, Temmesfeld A, Schmitz R, Rübe C, Probst A, Jaenke G, Bodenstein H, Junker A, Pott C, Schultze J, Heinecke A, Parwaresch R, Tiemann M. Primary gastrointestinal non-Hodgkin's lymphoma: I. Anatomic and histologic distribution, clinical features, and survival data of 371 patients registered in the German Multicenter Study GIT NHL 01/92. J Clin Oncol. 2001 Sep 15; 19(18):3861-73. PMID: 11559724.
      Citations:    
    227. Koch P, del Valle F, Berdel WE, Willich NA, Reers B, Hiddemann W, Grothaus-Pinke B, Reinartz G, Brockmann J, Temmesfeld A, Schmitz R, Rübe C, Probst A, Jaenke G, Bodenstein H, Junker A, Pott C, Schultze J, Heinecke A, Parwaresch R, Tiemann M. Primary gastrointestinal non-Hodgkin's lymphoma: II. Combined surgical and conservative or conservative management only in localized gastric lymphoma--results of the prospective German Multicenter Study GIT NHL 01/92. J Clin Oncol. 2001 Sep 15; 19(18):3874-83. PMID: 11559725.
      Citations:    
    228. Schultze JL, Vonderheide RH. From cancer genomics to cancer immunotherapy: toward second-generation tumor antigens. Trends Immunol. 2001 Sep; 22(9):516-23. PMID: 11525943.
      Citations:    
    229. Trojan A, Witzens M, Schultze JL, Vonderheide RH, Harig S, Krackhardt AM, Stahel RA, Gribben JG. Generation of cytotoxic T lymphocytes against native and altered peptides of human leukocyte antigen-A*0201 restricted epitopes from the human epithelial cell adhesion molecule. Cancer Res. 2001 Jun 15; 61(12):4761-5. PMID: 11406549.
      Citations:    
    230. Schultze JL, Anderson KC, Gilleece MH, Gribben JG, Nadler LM. A pilot study of combined immunotherapy with autologous adoptive tumour-specific T-cell transfer, vaccination with CD40-activated malignant B cells and interleukin 2. Br J Haematol. 2001 May; 113(2):455-60. PMID: 11380416.
      Citations:    
    231. Schultze JL, Maecker B, von Bergwelt-Baildon MS, Anderson KS, Vonderheide RH. Tumour immunotherapy: new tools, new treatment modalities and new T-cell antigens. Vox Sang. 2001 Feb; 80(2):81-9. PMID: 11378969.
      Citations:    
    232. Trojan A, Schultze JL, Witzens M, Vonderheide RH, Ladetto M, Donovan JW, Gribben JG. Immunoglobulin framework-derived peptides function as cytotoxic T-cell epitopes commonly expressed in B-cell malignancies. Nat Med. 2000 Jun; 6(6):667-72. PMID: 10835683.
      Citations:    
    233. Anton JV, Schultze J, Gstöttner W, Matula C. [Tumors of the anterior skull base. Effects of perioperative imaging on adjuvant radiotherapy planning]. Rontgenpraxis. 2000; 53(1):10-5. PMID: 10943137.
      Citations:    
    234. Schultze J, Kaya A, Kimmig B. [Results of radiotherapy in brain metastasis]. Rontgenpraxis. 2000; 53(3):102-9. PMID: 11131110.
      Citations:    
    235. Schultze J, Johnson P. A stimulating new target for cancer immunotherapy. Lancet. 1999 Oct 09; 354(9186):1225-7. PMID: 10520628.
      Citations:    
    236. Vonderheide RH, Hahn WC, Schultze JL, Nadler LM. The telomerase catalytic subunit is a widely expressed tumor-associated antigen recognized by cytotoxic T lymphocytes. Immunity. 1999 Jun; 10(6):673-9. PMID: 10403642.
      Citations:    
    237. Schultze JL, Nadler LM. T cell mediated immunotherapy for B cell lymphoma. J Mol Med (Berl). 1999 Mar; 77(3):322-31. PMID: 10090595.
      Citations:    
    238. Schultze JL, Donovan JW, Gribben JG. Minimal residual disease detection after myeloablative chemotherapy in chronic lymphatic leukemia. J Mol Med (Berl). 1999 Feb; 77(2):259-65. PMID: 10023779.
      Citations:    
    239. Schultze JL, Michalak S, Lowne J, Wong A, Gilleece MH, Gribben JG, Nadler LM. Human non-germinal center B cell interleukin (IL)-12 production is primarily regulated by T cell signals CD40 ligand, interferon gamma, and IL-10: role of B cells in the maintenance of T cell responses. J Exp Med. 1999 Jan 04; 189(1):1-12. PMID: 9874559.
      Citations:    
    240. Hart DN, Schultze JL, Stewart AK. Presentation of tumor antigens. Semin Hematol. 1999 Jan; 36(1 Suppl 3):21-5. PMID: 9989485.
      Citations:    
    241. Schultze JL. Why do B cell lymphoma fail to elicit clinically sufficient T cell immune responses? Leuk Lymphoma. 1999 Jan; 32(3-4):223-36. PMID: 10037020.
      Citations:    
    242. Schultze JL, Gribben JG, Nadler LM. Tumor-specific adoptive T-cell therapy for CD40+ B-cell malignancies. Curr Opin Oncol. 1998 Nov; 10(6):542-7. PMID: 9818233.
      Citations:    
    243. Bleul CC, Schultze JL, Springer TA. B lymphocyte chemotaxis regulated in association with microanatomic localization, differentiation state, and B cell receptor engagement. J Exp Med. 1998 Mar 02; 187(5):753-62. PMID: 9480985.
      Citations:    
    244. Ghia P, Boussiotis VA, Schultze JL, Cardoso AA, Dorfman DM, Gribben JG, Freedman AS, Nadler LM. Unbalanced expression of bcl-2 family proteins in follicular lymphoma: contribution of CD40 signaling in promoting survival. Blood. 1998 Jan 01; 91(1):244-51. PMID: 9414291.
      Citations:    
    245. Dorfman DM, Schultze JL, Shahsafaei A, Michalak S, Gribben JG, Freeman GJ, Pinkus GS, Nadler LM. In vivo expression of B7-1 and B7-2 by follicular lymphoma cells can prevent induction of T-cell anergy but is insufficient to induce significant T-cell proliferation. Blood. 1997 Dec 01; 90(11):4297-306. PMID: 9373240.
      Citations:    
    246. Schultze JL, Michalak S, Seamon MJ, Dranoff G, Jung K, Daley J, Delgado JC, Gribben JG, Nadler LM. CD40-activated human B cells: an alternative source of highly efficient antigen presenting cells to generate autologous antigen-specific T cells for adoptive immunotherapy. J Clin Invest. 1997 Dec 01; 100(11):2757-65. PMID: 9389740.
      Citations:    
    247. Schultze JL. Vaccination as immunotherapy for B cell lymphoma. Hematol Oncol. 1997 Aug; 15(3):129-39. PMID: 9600112.
      Citations:    
    248. Schultze JL, Seamon MJ, Michalak S, Gribben JG, Nadler LM. Autologous tumor infiltrating T cells cytotoxic for follicular lymphoma cells can be expanded in vitro. Blood. 1997 May 15; 89(10):3806-16. PMID: 9160688.
      Citations:    
    249. Gribben JG, Cardoso AA, Schultze JL, Nadler LM. Biologic response modifiers in acute lymphoblastic leukemia. Leukemia. 1997 May; 11 Suppl 4:S31-3. PMID: 9179280.
      Citations:    
    250. Gribben JG, Schultze JL. The detection of minimal residual disease: implications for bone marrow transplantation. Cancer Treat Res. 1997; 77:99-120. PMID: 9071500.
      Citations:    
    251. Hall KT, Boumsell L, Schultze JL, Boussiotis VA, Dorfman DM, Cardoso AA, Bensussan A, Nadler LM, Freeman GJ. Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation. Proc Natl Acad Sci U S A. 1996 Oct 15; 93(21):11780-5. PMID: 8876214.
      Citations:    
    252. Cardoso AA, Schultze JL, Boussiotis VA, Freeman GJ, Seamon MJ, Laszlo S, Billet A, Sallan SE, Gribben JG, Nadler LM. Pre-B acute lymphoblastic leukemia cells may induce T-cell anergy to alloantigen. Blood. 1996 Jul 01; 88(1):41-8. PMID: 8704200.
      Citations:    
    253. Schultze J, Nadler LM, Gribben JG. B7-mediated costimulation and the immune response. Blood Rev. 1996 Jun; 10(2):111-27. PMID: 8813343.
      Citations:    
    254. Schultze JL, Gribben JG. Minimal residual disease in non-Hodgkin's lymphoma. Biomed Pharmacother. 1996; 50(9):451-8. PMID: 8991117.
      Citations:    
    255. Schultze JL, Cardoso AA, Freeman GJ, Seamon MJ, Daley J, Pinkus GS, Gribben JG, Nadler LM. Follicular lymphomas can be induced to present alloantigen efficiently: a conceptual model to improve their tumor immunogenicity. Proc Natl Acad Sci U S A. 1995 Aug 29; 92(18):8200-4. PMID: 7545296.
      Citations:    
    256. Veelken H, Jesuiter H, Mackensen A, Kulmburg P, Schultze J, Rosenthal F, Mertelsmann R, Lindemann A. Primary fibroblasts from human adults as target cells for ex vivo transfection and gene therapy. Hum Gene Ther. 1994 Oct; 5(10):1203-10. PMID: 7849093.
      Citations:    
    257. Digel W, Schultze J, Kunzmann R, Mertelsmann R, Lindemann A. Poor prognosis of prethymic phenotype acute lymphoblastic leukemia (pre-T-ALL). Leukemia. 1994 Aug; 8(8):1406-8. PMID: 8057681.
      Citations:    
    258. Schultze JL, Stettin A, Berg PA. Demonstration of specifically sensitized lymphocytes in patients treated with an aqueous mistletoe extract (Viscum album L.). Klin Wochenschr. 1991 Jun 18; 69(9):397-403. PMID: 1921242.
      Citations:    
    259. Stettin A, Schultze JL, Stechemesser E, Berg PA. Anti-mistletoe lectin antibodies are produced in patients during therapy with an aqueous mistletoe extract derived from Viscum album L. and neutralize lectin-induced cytotoxicity in vitro. Klin Wochenschr. 1990 Sep 14; 68(18):896-900. PMID: 2124308.
      Citations:    
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