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Thomas Wiehe

TitleProf.
InstitutionUniversity of Cologne
DepartmentBiologie, Genetik
AddressCologne 50674
Phone+49 2214701588
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Heger P, Zheng W, Rottmann A, Panfilio KA, Wiehe T. The genetic factors of bilaterian evolution. Elife. 2020 Jul 16; 9. PMID: 32672535.
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    2. Disanto F, Wiehe T. Measuring the external branches of a Kingman tree: A discrete approach. Theor Popul Biol. 2020 Aug; 134:92-105. PMID: 32485202.
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    3. Suurväli J, Whiteley AR, Zheng Y, Gharbi K, Leptin M, Wiehe T. The Laboratory Domestication of Zebrafish: From Diverse Populations to Inbred Substrains. Mol Biol Evol. 2020 04 01; 37(4):1056-1069. PMID: 31808937.
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    4. Zheng Y, Wiehe T. Adaptation in structured populations and fuzzy boundaries between hard and soft sweeps. PLoS Comput Biol. 2019 11; 15(11):e1007426. PMID: 31710623.
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    5. Schiffer PH, Danchin EGJ, Burnell AM, Creevey CJ, Wong S, Dix I, O'Mahony G, Culleton BA, Rancurel C, Stier G, Martínez-Salazar EA, Marconi A, Trivedi U, Kroiher M, Thorne MAS, Schierenberg E, Wiehe T, Blaxter M. Signatures of the Evolution of Parthenogenesis and Cryptobiosis in the Genomes of Panagrolaimid Nematodes. iScience. 2019 Nov 22; 21:587-602. PMID: 31759330.
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    6. Jabbari K, Chakraborty M, Wiehe T. DNA sequence-dependent chromatin architecture and nuclear hubs formation. Sci Rep. 2019 10 10; 9(1):14646. PMID: 31601866.
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    7. Wirtz J, Wiehe T. The Evolving Moran Genealogy. Theor Popul Biol. 2019 12; 130:94-105. PMID: 31330138.
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    8. Jabbari K, Wirtz J, Rauscher M, Wiehe T. A common genomic code for chromatin architecture and recombination landscape. PLoS One. 2019; 14(3):e0213278. PMID: 30865674.
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    9. Wirtz J, Rauscher M, Wiehe T. Topological linkage disequilibrium calculated from coalescent genealogies. Theor Popul Biol. 2018 12; 124:41-50. PMID: 30243857.
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    10. Ferretti L, Klassmann A, Raineri E, Ramos-Onsins SE, Wiehe T, Achaz G. The neutral frequency spectrum of linked sites. Theor Popul Biol. 2018 09; 123:70-79. PMID: 29964061.
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    11. Jabbari K, Heger P, Sharma R, Wiehe T. The Diverging Routes of BORIS and CTCF: An Interactomic and Phylogenomic Analysis. Life (Basel). 2018 Jan 30; 8(1). PMID: 29385718.
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    12. Yang Z, Li J, Wiehe T, Li H. Detecting Recent Positive Selection with a Single Locus Test Bipartitioning the Coalescent Tree. Genetics. 2018 02; 208(2):791-805. PMID: 29217523.
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    13. Ferretti L, Ledda A, Wiehe T, Achaz G, Ramos-Onsins SE. Decomposing the Site Frequency Spectrum: The Impact of Tree Topology on Neutrality Tests. Genetics. 2017 09; 207(1):229-240. PMID: 28679545.
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    14. Pauli T, Vedder L, Dowling D, Petersen M, Meusemann K, Donath A, Peters RS, Podsiadlowski L, Mayer C, Liu S, Zhou X, Heger P, Wiehe T, Hering L, Mayer G, Misof B, Niehuis O. Transcriptomic data from panarthropods shed new light on the evolution of insulator binding proteins in insects : Insect insulator proteins. BMC Genomics. 2016 Nov 03; 17(1):861. PMID: 27809783.
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    15. Schiffer PH, Gravemeyer J, Rauscher M, Wiehe T. Ultra Large Gene Families: A Matter of Adaptation or Genomic Parasites? Life (Basel). 2016 Aug 08; 6(3). PMID: 27509525.
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    16. Howe K, Schiffer PH, Zielinski J, Wiehe T, Laird GK, Marioni JC, Soylemez O, Kondrashov F, Leptin M. Structure and evolutionary history of a large family of NLR proteins in the zebrafish. Open Biol. 2016 Apr; 6(4):160009. PMID: 27248802.
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    17. Heger P, Wiehe T. New tools in the box: an evolutionary synopsis of chromatin insulators. Trends Genet. 2014 May; 30(5):161-71. PMID: 24786278.
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    18. Disanto F, Schlizio A, Wiehe T. Yule-generated trees constrained by node imbalance. Math Biosci. 2013 Nov; 246(1):139-47. PMID: 23994240.
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    19. Heger P, George R, Wiehe T. Successive gain of insulator proteins in arthropod evolution. Evolution. 2013 Oct; 67(10):2945-56. PMID: 24094345.
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    20. Li H, Wiehe T. Coalescent tree imbalance and a simple test for selective sweeps based on microsatellite variation. PLoS Comput Biol. 2013; 9(5):e1003060. PMID: 23696722.
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    21. Ferretti L, Disanto F, Wiehe T. The effect of single recombination events on coalescent tree height and shape. PLoS One. 2013; 8(4):e60123. PMID: 23593168.
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    22. Disanto F, Wiehe T. Exact enumeration of cherries and pitchforks in ranked trees under the coalescent model. Math Biosci. 2013 Apr; 242(2):195-200. PMID: 23396093.
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    23. Heger P, Marin B, Bartkuhn M, Schierenberg E, Wiehe T. The chromatin insulator CTCF and the emergence of metazoan diversity. Proc Natl Acad Sci U S A. 2012 Oct 23; 109(43):17507-12. PMID: 23045651.
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    24. Haubold B, Pfaffelhuber P, Domazet-Loso M, Wiehe T. Estimating mutation distances from unaligned genomes. J Comput Biol. 2009 Oct; 16(10):1487-500. PMID: 19803738.
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    25. Kim Y, Wiehe T. Simulation of DNA sequence evolution under models of recent directional selection. Brief Bioinform. 2009 Jan; 10(1):84-96. PMID: 19109303.
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    26. Teschke M, Mukabayire O, Wiehe T, Tautz D. Identification of selective sweeps in closely related populations of the house mouse based on microsatellite scans. Genetics. 2008 Nov; 180(3):1537-45. PMID: 18791245.
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    27. Zivkovic D, Wiehe T. Second-order moments of segregating sites under variable population size. Genetics. 2008 Sep; 180(1):341-57. PMID: 18716326.
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    28. Vukusic I, Grellscheid SN, Wiehe T. Applying genetic programming to the prediction of alternative mRNA splice variants. Genomics. 2007 Apr; 89(4):471-9. PMID: 17276654.
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    29. Stephan M, Möller F, Wiehe T, Kleffe J. Self-alignments to detect mutually exclusive exon usage. In Silico Biol. 2007; 7(6):613-21. PMID: 18467774.
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    30. Haubold B, Wiehe T. How repetitive are genomes? BMC Bioinformatics. 2006 Dec 22; 7:541. PMID: 17187668.
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    31. Wiehe T, Nolte V, Zivkovic D, Schlötterer C. Identification of selective sweeps using a dynamically adjusted number of linked microsatellites. Genetics. 2007 Jan; 175(1):207-18. PMID: 17057237.
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    32. Pierstorff N, Bergman CM, Wiehe T. Identifying cis-regulatory modules by combining comparative and compositional analysis of DNA. Bioinformatics. 2006 Dec 01; 22(23):2858-64. PMID: 17032682.
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    33. Haubold B, Pierstorff N, Möller F, Wiehe T. Genome comparison without alignment using shortest unique substrings. BMC Bioinformatics. 2005 May 23; 6:123. PMID: 15910684.
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    34. Haubold B, Wiehe T. Comparative genomics: methods and applications. Naturwissenschaften. 2004 Sep; 91(9):405-21. PMID: 15278216.
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    35. Abril JF, Guigó R, Wiehe T. gff2aplot: Plotting sequence comparisons. Bioinformatics. 2003 Dec 12; 19(18):2477-9. PMID: 14668236.
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    36. Parra G, Agarwal P, Abril JF, Wiehe T, Fickett JW, Guigó R. Comparative gene prediction in human and mouse. Genome Res. 2003 Jan; 13(1):108-17. PMID: 12529313.
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    37. Haubold B, Kroymann J, Ratzka A, Mitchell-Olds T, Wiehe T. Recombination and gene conversion in a 170-kb genomic region of Arabidopsis thaliana. Genetics. 2002 Jul; 161(3):1269-78. PMID: 12136029.
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    38. Haubold B, Wiehe T. Calculating the SNP-effective sample size from an alignment. Bioinformatics. 2002 Jan; 18(1):36-8. PMID: 11836209.
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    39. Wiehe TH, Stephan W. Analysis of a genetic hitchhiking model, and its application to DNA polymorphism data from Drosophila melanogaster. Mol Biol Evol. 1993 Jul; 10(4):842-54. PMID: 8355603.
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